Objective To investigate the changes of multifocal electroretinogram (mf-ERG) in type 2 diabetes without clinically apparent retinopathy. Methods Eighteen type 2 diabetes patients (32 eyes) without clinically observed retinopathy and 14 normal control eyes received mfERG examination. Results The latency of P1 wave in the ring one, ring two and ring three of diabetes were (48.47±2.33), (31.19±15.53), (15.67±5.73) ms respectively, which had significantly statistical difference with the normal control eyes (t=5.145，2.376，2.276；P＜0.05). The amplitude density of P1 wave of temporal retina in diabetes patients was (9.07±2.19) nV/deg2,which was significant different （t=-3.468,P＜0.05） with the normal control eyes (14.13±2.76) nV/deg2. Conclusion The latency of mf-ERG P1 wave is delayed, and the amplitude density of P1 wave of temporal retina is declined in type 2 diabetes patients without clinically apparent retinopathy.
Citation： 黄江,徐国旭,魏晓红,季晓燕,金吉. Characteristics of the multifocal electroretinogram in type 2 diabetes without clinically apparent retinopathy. Chinese Journal of Ocular Fundus Diseases, 2013, 29(5): 487-489. doi: Copy