• Research Institute of Field Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042,China;
Optic nerve Injury; Nerve growth factor/antagonists & inhibitors; Reverse transcritase polymerase chain reaction; Disease models, animol
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Objective To evaluate the expressive varieties of Nogo-A mRNA in injured optic nerves of rats. Methods Reverse transcription polymerase chain reaction (RT-PCR) method was used to hemi-quantitatively analyze the levels of Nogo-A mRNA in the optic nerves 3, 7, 9, 15, 21, and 25 days respectively after injury.Results The level of the expression of Nogo-A mRNA was low in the normal optic nerves, while it was significantly high in the optic nerves 3 days after in jury, and kept the high level still after 25 days.Conclusion The expression of Nogo-A mRNA in injured optic nerves is increased. (Chin J Ocul Fundus Dis，2003，19：201-268)

Citation： YE Jian,WANG Zhengguo,ZHU Peifang. Expressive varieties of Nogo-A mRNA in injured optic nerves. Chinese Journal of Ocular Fundus Diseases, 2003, 19(4): 247-249. doi: Copy