Cai Jiping , Zhou Yunqiu , Xi Shouzeng
  • Department of Ophthalmology,changzheng Hospital,Second Military Medical University,Shanghai 20003,China;
Epidermal growth factor-urogastrone; Retina; Nerve growth factors; Cell,cultured
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Objective:To study the effects of growth factor on the proliferation of the cultured huamn retinal glial cells. Methods:EGF(0.5～100.0ng/ml) and NGF (0.5～10.0ng/ml) were added to cultures of human retinal glial cells and the proliferation rates of the cells were measured by MTT method. Results:EGF at a dosage ranging from 0.5ng/ml to 100.0ng/ml and NGF (0.05～10.0ng/ml) stimulated the cellular proliferation effectively with their EC 50 of 17ng/ml and 0.7 ng/ml respectively. Conclusion:Both EGF and NGF NGF had an effective stimulation on human retinal glial cell proliferation.They may play a role in the formation of PVR. (Chin J Ocul Fundus Dis,1998,14:33-34)

Citation： Cai Jiping,Zhou Yunqiu,Xi Shouzeng. Growth factor effects on the proliferation of human retinal glial cell in culture. Chinese Journal of Ocular Fundus Diseases, 1998, 14(1): 33-34. doi: Copy