In order to explore the histochemical changes in retina after intravitreal injection of gentamycin,a histochemical quantitative analysis of cytochrome oxidase(CYO)and acetylcholinesterase(ACHE)was performed with a computerized image analysis system and was compared with that of morphological study.The results showed that CYO decreased significantly in 100 mu;g dosage group.With increasing intravitreal gentamycin dosage or observed days,CYO decreased gradually in all rabbits.In 100~500 mu;g dosage groups,ACHE changed mildly at 3 days of injection.It decreased significantly at 7 days.However,it was destroyed completely in 1000~3000 mu;g dosage groups at 3 days. （Chin J Ocul Fundus Dis,1994,10:232-235）
Citation： Wang Danmei,Zhu Xiuan,Li Fengming,et al.. RETINAL TOXICITY OF INTRAVITREAL GENTAMYCIN IN RABBITS Ⅱ.A HISTOCHEMICAL QUANTITATIVE ANALYSIS. Chinese Journal of Ocular Fundus Diseases, 1994, 10(4): 232-235. doi: Copy