Acupuncture for Mammary Dysplasia: A Systematic Review_Chinese Journal of Evidence-Based Medicine

Authors：

YU Jinna ¹ , LIU Baoyan ² , LIU Zhishun ¹ , CHEN Xiaoyan. . Acupuncture Department ³

1. Acupuncture Department; Guang’an Men Hospital Affiliated to China Academy of Traditional Chinese Medicine; Beijing 100053; China2. China Academy of Traditional Chinese Medicine; Beijing 1007003. Seven-year class; Grade 2000; West China Medical Center; Sichuan University; Chengdu 610041;

Corresponding author：

Keywords：

Acupuncture; Mammary dysplasia; Systematic review

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Objective 　To assess the effectiveness and safety of various types of acupuncture in the treatment of mammary dysplasia.
Methods 　We searched The Cochrane Library, CENTRAL, MEDLINE (1966 to 2004), EMBASE (1980 to 2004), CBM (1975 to 2004), CNKI (1997 to 2004) and reference lists, databases of ongoing trials and relevent academic conference proceedings.
Results 　Five studies involving 534 women ranging from 78 to 180 met the inclusion criteria. The recovery rates of two groups in one study showed acupuncture was statistically superior to Rupixiao (RR 9.00, 95%CI 2.29 to 35.43; RR 8.04, 95%CI 2.20 to 32.02), six good improvement rates (including groups analysis) indicated that there was no significant difference between acupuncture and other therapies. None of the studies reported incidence of adverse reaction.
Conclusions 　Overall, there is no conclusive evidence for acupuncture in the treatment of mammary dysplasia because the quality of included studies and amount of evidence are both poor and insufficient. There is an urgent need for larger, well-designed randomised controlled trials to assess the effectiveness and adverse-effect of acupuncture.

Citation： YU Jinna,LIU Baoyan,LIU Zhishun,CHEN Xiaoyan. . Acupuncture Department,Guangan Men Hospital Affiliated to China Academy of Traditional Chinese Medicine,Beijing,China,. China Academy of Traditional Chinese Medicine,Beijing,. Sevenyear class,Grade,West China Medical Center,Sichuan University,Chengdu. Acupuncture for Mammary Dysplasia: A Systematic Review. Chinese Journal of Evidence-Based Medicine, 2005, 05(5): 381-385. doi: Copy

1.	马丽华, 主编. 乳腺疾病比较影像诊断学[M]. 第1版. 北京: 军事医学科学出版社; 2003.
2.	刘丽军,李金发,杜冬,韩晨燕,李炎高择日电针治疗乳腺增生病的临床观察[J]中国针灸1996;16(4):7～8.
3.	龚东方,杨海燕,李素荷针药结合治疗乳腺增生症的临床观察与研究[J]针刺研究,1997;22(4):271～273.
4.	王玉慧,杨沈秋,马国庆内服小金丸配合针刺背俞穴治疗乳腺小叶增生病疗效观察[J].黑龙江医学,2003;27(6):441～ 442.
5.	吕大鸣,贾桂芹,陈双文针刺配合中药治疗乳腺增生39例[J]中国针灸,1996;l6(6):5.
6.	James P. Fibrocystic breast disease[EB/OL]. Available from: URL: http://www.umm.edu/ency/article/000912.htm.
7.	NCBI. Fibrocystic Disease of Breast[EB/OL]. Available from: URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=mesh&list_uids=68005348&dopt=Full.
8.	Ma LH, ed. Comparision Image Diagnostics in Breast Diseasev[M]. 1st ed. Beijing: Military Medicine Science Press; 2003.
9.	Berek JS. Novak’s gynecology[M]. 13th ed. Philadelphia: Lippincott Williams & Wilkins; 2002.
10.	Hutter RVP. Is fibrocystic disease of the precancerous[J]? Arch Pathol Lab Med, 1986; 110(3): 171-173.
11.	London SJ, Connolly JL, Schnitt SJ, Colditz. A prospective study of benigh breast disease and the risk of breast cancer[J]. JAMA, 1992; 267(7): 941-944.
12.	Page DL, Dupont WD. Anatomic markers of human premalignancy and risk of breast cancer[J]. Cancer, 1990; 66(6 supplement): 1 326-1 335.
13.	Page Dl. The woman at high risk for breast cancer: importance of hyperplasia[J]. Surg Clin North Am, 1996; 76(2): 223-230.
14.	Simpson JF, Page Dl. Pathology of preinvasive and excellent-prognosis breast cancer[J]. Curr Opin Oncol, 1997; 9(6): 512-519.
15.	Mansel RE, Harrison BJ, Melhuish J, Sheridan W, Pye JK, Pritchard G, Maddox PR, Webster DJ, Hughes LE. A randomised trial of dietary intervention with essential fatty acids in patients with categorized cysts[J]. Ann N Y Acad Sci, 1990; 586: 288-294.
16.	Lv Meizhen. Clinical search of combination electro-acupuncture at Jiaji and acupuncture at Renying to treat mammary dysplasia[J]. Journal of Shandong university of TCM, 2004; 28(3): 214-216, 219.
17.	Dixon JM. Cystic disease and fibroadenoma of the breast: natural history and relation to breast cancer risk[J]. Br Med Bull, 1991; 47(2): 258-271.
18.	FRED. Fibrocystic Disease of Breast[EB/OL]. Available from: URL: http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D005348.
19.	Maddox PR, Mansel RE. Management of breast pain and nodularit[J]. World J Surg, 1989; 13(6): 699-705.
20.	Stovall, Thomas G. Clinical Manual of Gynecology[M]. 2nd ed. New York: McGraw-Hill, Inc; 1992.
21.	Faiz O, Fentiman IS. Management of breast pain[J]. Int J Clin Pract, 2002; 54(4): 228-232.
22.	Gateley CA, Miers M, Mansel RE, Huges LE. Drug treatments for mastalgia: 17 year experience in the Cardiff Mastalgia Clinic[J]. J R Soc Med, 1992; 85(1): 12-15.
23.	Rea N, Bove F, Gentile A, Parmeggiani U. Prolactin response to thyrotropin-releasing hormone as a guideline for cyclical mastalgia[J]. Gynecol Endocrinol, 1997; 88(11): 479-487.
24.	Kontostolis E, Stefanidis K, Navrozoglou I, Lolis D. Comparison of tamoxifen with danazol for treatment of cyclical mastalgia[J]. Gynecol Endocrinol, 1997; 11(6): 393-397.
25.	Holland PA, Gateley CA. Drug therapy of mastalaia. What are the options[J]? Drugs, 1994; 48(5): 709-716.
26.	London RS, Sundaram GS, Murphy L, Murphy L, Goldstein PJ. The effect of a-tocopherol on premenstrual symptomology a double-blind study[J]. J Am Coll Nutr, 1983; 2(2): 115-122.
27.	Abraham GE, Nutritional factors in the etiology of the premenstrual tention syndromes[J]. J Reprod Med, 1983; 28(7): 446-464.
28.	Schulz KF, Chalmers I, Hayes RJ, Altman DG. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials[J]. JAMA, 1995; 273(5): 408-412.
29.	Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ. Assessing the quality of reports of randomized clinical trials: is blinding necessary [J ] ? Control Clin Trials, 1996; 17(1): 1-12.
30.	Moher D, Pham B, Jones AR, Cook DJ, Jadad A, Moher M,Tugwell P, Klassen TP. Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analysis[J].Lancet, 1998; 352(9128): 609-613.
31.	Juni P, Altman DG, Egger M. Systematic reviews in health care:Assessing the quality of controlled clinical trials[J ]. BM J, 2001; 323(7303): 42 -46.
32.	Kjaergard LL, Villumsen J, Gluud C. Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses[J]. Ann Intern Med, 2001; 135( 11 ): 982 -989.
33.	Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test [ J ] v BM J, 1997; 315 (7109): 629 -634.
34.	Liu LJ, LiJF, Du D, Han CY, Li YG. Clinical observation of electro-acupuncture on selective date in treating mammary dysplasia [J ].Chinese Acupuncture & Moxibustion, 1996; 16 ( 4 ): 7 - 8.
35.	Gong DF, Yang HY, Li SH. Clinical observation and study: acupuncture in conjunction with medicine to treat mammary dysplasia[J]Acupuncture research, 1997; 22(4): 271 -273.
36.	Wang YH, Yang SQ, Ma GQ. Curative effect observation of Xiao jinwan combined with acupuncture at Beishu in treating mammary dysplasia[J]. Hei Long Jiang Medical Journal, 2003; 27(6): 441 -442.
37.	Lv DM, Jia GQ, Chen SW. Acupuncture combined with Chinese herbs to treat 39 patients with mammary dysplasia[J ]. Chinese Acupuncture & Moxibustion, 1996; 16(6): 5.

1. 马丽华, 主编. 乳腺疾病比较影像诊断学[M]. 第1版. 北京: 军事医学科学出版社; 2003.
2. 刘丽军,李金发,杜冬,韩晨燕,李炎高择日电针治疗乳腺增生病的临床观察[J]中国针灸1996;16(4):7～8.
3. 龚东方,杨海燕,李素荷针药结合治疗乳腺增生症的临床观察与研究[J]针刺研究,1997;22(4):271～273.
4. 王玉慧,杨沈秋,马国庆内服小金丸配合针刺背俞穴治疗乳腺小叶增生病疗效观察[J].黑龙江医学,2003;27(6):441～ 442.
5. 吕大鸣,贾桂芹,陈双文针刺配合中药治疗乳腺增生39例[J]中国针灸,1996;l6(6):5.
6. James P. Fibrocystic breast disease[EB/OL]. Available from: URL: http://www.umm.edu/ency/article/000912.htm.
7. NCBI. Fibrocystic Disease of Breast[EB/OL]. Available from: URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=mesh&list_uids=68005348&dopt=Full.
8. Ma LH, ed. Comparision Image Diagnostics in Breast Diseasev[M]. 1st ed. Beijing: Military Medicine Science Press; 2003.
9. Berek JS. Novak’s gynecology[M]. 13th ed. Philadelphia: Lippincott Williams & Wilkins; 2002.
10. Hutter RVP. Is fibrocystic disease of the precancerous[J]? Arch Pathol Lab Med, 1986; 110(3): 171-173.
11. London SJ, Connolly JL, Schnitt SJ, Colditz. A prospective study of benigh breast disease and the risk of breast cancer[J]. JAMA, 1992; 267(7): 941-944.
12. Page DL, Dupont WD. Anatomic markers of human premalignancy and risk of breast cancer[J]. Cancer, 1990; 66(6 supplement): 1 326-1 335.
13. Page Dl. The woman at high risk for breast cancer: importance of hyperplasia[J]. Surg Clin North Am, 1996; 76(2): 223-230.
14. Simpson JF, Page Dl. Pathology of preinvasive and excellent-prognosis breast cancer[J]. Curr Opin Oncol, 1997; 9(6): 512-519.
15. Mansel RE, Harrison BJ, Melhuish J, Sheridan W, Pye JK, Pritchard G, Maddox PR, Webster DJ, Hughes LE. A randomised trial of dietary intervention with essential fatty acids in patients with categorized cysts[J]. Ann N Y Acad Sci, 1990; 586: 288-294.
16. Lv Meizhen. Clinical search of combination electro-acupuncture at Jiaji and acupuncture at Renying to treat mammary dysplasia[J]. Journal of Shandong university of TCM, 2004; 28(3): 214-216, 219.
17. Dixon JM. Cystic disease and fibroadenoma of the breast: natural history and relation to breast cancer risk[J]. Br Med Bull, 1991; 47(2): 258-271.
18. FRED. Fibrocystic Disease of Breast[EB/OL]. Available from: URL: http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D005348.
19. Maddox PR, Mansel RE. Management of breast pain and nodularit[J]. World J Surg, 1989; 13(6): 699-705.
20. Stovall, Thomas G. Clinical Manual of Gynecology[M]. 2nd ed. New York: McGraw-Hill, Inc; 1992.
21. Faiz O, Fentiman IS. Management of breast pain[J]. Int J Clin Pract, 2002; 54(4): 228-232.
22. Gateley CA, Miers M, Mansel RE, Huges LE. Drug treatments for mastalgia: 17 year experience in the Cardiff Mastalgia Clinic[J]. J R Soc Med, 1992; 85(1): 12-15.
23. Rea N, Bove F, Gentile A, Parmeggiani U. Prolactin response to thyrotropin-releasing hormone as a guideline for cyclical mastalgia[J]. Gynecol Endocrinol, 1997; 88(11): 479-487.
24. Kontostolis E, Stefanidis K, Navrozoglou I, Lolis D. Comparison of tamoxifen with danazol for treatment of cyclical mastalgia[J]. Gynecol Endocrinol, 1997; 11(6): 393-397.
25. Holland PA, Gateley CA. Drug therapy of mastalaia. What are the options[J]? Drugs, 1994; 48(5): 709-716.
26. London RS, Sundaram GS, Murphy L, Murphy L, Goldstein PJ. The effect of a-tocopherol on premenstrual symptomology a double-blind study[J]. J Am Coll Nutr, 1983; 2(2): 115-122.
27. Abraham GE, Nutritional factors in the etiology of the premenstrual tention syndromes[J]. J Reprod Med, 1983; 28(7): 446-464.
28. Schulz KF, Chalmers I, Hayes RJ, Altman DG. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials[J]. JAMA, 1995; 273(5): 408-412.
29. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ. Assessing the quality of reports of randomized clinical trials: is blinding necessary [J ] ? Control Clin Trials, 1996; 17(1): 1-12.
30. Moher D, Pham B, Jones AR, Cook DJ, Jadad A, Moher M,Tugwell P, Klassen TP. Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analysis[J].Lancet, 1998; 352(9128): 609-613.
31. Juni P, Altman DG, Egger M. Systematic reviews in health care:Assessing the quality of controlled clinical trials[J ]. BM J, 2001; 323(7303): 42 -46.
32. Kjaergard LL, Villumsen J, Gluud C. Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses[J]. Ann Intern Med, 2001; 135( 11 ): 982 -989.
33. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test [ J ] v BM J, 1997; 315 (7109): 629 -634.
34. Liu LJ, LiJF, Du D, Han CY, Li YG. Clinical observation of electro-acupuncture on selective date in treating mammary dysplasia [J ].Chinese Acupuncture & Moxibustion, 1996; 16 ( 4 ): 7 - 8.
35. Gong DF, Yang HY, Li SH. Clinical observation and study: acupuncture in conjunction with medicine to treat mammary dysplasia[J]Acupuncture research, 1997; 22(4): 271 -273.
36. Wang YH, Yang SQ, Ma GQ. Curative effect observation of Xiao jinwan combined with acupuncture at Beishu in treating mammary dysplasia[J]. Hei Long Jiang Medical Journal, 2003; 27(6): 441 -442.
37. Lv DM, Jia GQ, Chen SW. Acupuncture combined with Chinese herbs to treat 39 patients with mammary dysplasia[J ]. Chinese Acupuncture & Moxibustion, 1996; 16(6): 5.

Chinese Journal of Evidence-Based Medicine

Acupuncture for Mammary Dysplasia: A Systematic Review

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