How to Conduct A Systematic Review/Meta-analysis for Observational Studies_Chinese Journal of Evidence-Based Medicine

Authors：

WU Taixiang ¹ , LIU Guanjian ¹ , ZHAO Na ² , NI Juan ²

1. Chinese Clinical Epidemiology and Evidence-Based Medicine Centre; West China Hospital; Sichuan University; Chengdu 610041; China2. School of Clinical Medicine; West China Medical Centre; Sichuan University; Chengdu 610041; China;

Corresponding author：

Keywords：

Observational study; Systematic review; Meta-analysis; Methodology

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The necessity and methods of systematic review or Meta-analysis of observational studies were introduced. The difference between the systematic review or Meta-analysis of observational studies and randomized controlled trials was also described.

Citation： WU Taixiang,LIU Guanjian,ZHAO Na,NI Juan. How to Conduct A Systematic Review/Meta-analysis for Observational Studies. Chinese Journal of Evidence-Based Medicine, 2004, 04(5): 337-341. doi: Copy

1.	［1］Li YP, Wang L. Look forward to the 21 Century of Cochrane Collaboration [ J ]. Chinese Journal of Evidence-Based Medicine, 2001; 1 ( 1 ): 10 - 11.
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5.	［4］Blettner M, Sauerbrei W, Schlehofer B, Scheuchenpflug T,Friedenreich C. Traditional reviews, Meta-analysis and pooled analyses in epiderniology[J]. International Epidemiologycal Association, 1999; 28 ( 1 ): 1 - 9.
6.	［5］Thompson SG. Why sources of heterogeneity in Meta-analysis should be investigated [ J ]. Br Med J, 1994; 309 ( 6965 ):1 351-1 355.
7.	［6］Paul SR, Donner A. A comparison of tests of homogeneity of odds ratios in K2 ×2 tables[J]. Stat Med, 1989; 8(12):1 455-1 468.
8.	［7］Petitti DB. Meta-analysis, Decision Analysis and Cost-Effectiveness Analysis Methods for Quantitative Synthesis in Medicine [ M ]. New York, Oxford: Oxford University Press,1994.
9.	［8］Hedges LV, Olkin I. Statistical Methods for Meta-Analysis[M]. Orlando: Academic Press, 1985.
10.	［9］DerSimonian R, Laird N. Meta-analysis in chnical trials[J].Controlled Clin Trials, 1986; 7 (3) :177 - 188.
11.	［10］Greenland S. Quantitative methods in the review of epidemiology literature[J]. Epidem Rev ,1987; 9:1 -30.
12.	［11］Ollsson H. Oral contraceptives and breast cancer. A review[J]. Acta Oncol ,1989; 28(6):849-863.

1. ［1］Li YP, Wang L. Look forward to the 21 Century of Cochrane Collaboration [ J ]. Chinese Journal of Evidence-Based Medicine, 2001; 1 ( 1 ): 10 - 11.
2. 李幼平,王莉.Cochrane协作网21世纪展望[J].中国循证医学杂志,2001;1(1):10-11.
3. ［2］Stroup DF, Thacker SB, Olson CM, Glass RM. Characteristics of Meta-analysis submitted to a medical journal [ A].From: International Congress on Biomedical Peer Review and Global Communications [ M ]; Prague: Czech Republic,1997. 17-21.
4. ［3］Donna F. Stroup, Jesse A. Berlin, Sally C. Morton, Ingram Olkin, G. David Williamson, Drummond Rennie, David Moher, Betsy J. Becker, Theresa Ann Sipe, Stephen B.Thacker: Meta-analysis of observational studies in Epidemiology[J]. JAMA, 2000; 283(15) :2 008-2 012.
5. ［4］Blettner M, Sauerbrei W, Schlehofer B, Scheuchenpflug T,Friedenreich C. Traditional reviews, Meta-analysis and pooled analyses in epiderniology[J]. International Epidemiologycal Association, 1999; 28 ( 1 ): 1 - 9.
6. ［5］Thompson SG. Why sources of heterogeneity in Meta-analysis should be investigated [ J ]. Br Med J, 1994; 309 ( 6965 ):1 351-1 355.
7. ［6］Paul SR, Donner A. A comparison of tests of homogeneity of odds ratios in K2 ×2 tables[J]. Stat Med, 1989; 8(12):1 455-1 468.
8. ［7］Petitti DB. Meta-analysis, Decision Analysis and Cost-Effectiveness Analysis Methods for Quantitative Synthesis in Medicine [ M ]. New York, Oxford: Oxford University Press,1994.
9. ［8］Hedges LV, Olkin I. Statistical Methods for Meta-Analysis[M]. Orlando: Academic Press, 1985.
10. ［9］DerSimonian R, Laird N. Meta-analysis in chnical trials[J].Controlled Clin Trials, 1986; 7 (3) :177 - 188.
11. ［10］Greenland S. Quantitative methods in the review of epidemiology literature[J]. Epidem Rev ,1987; 9:1 -30.
12. ［11］Ollsson H. Oral contraceptives and breast cancer. A review[J]. Acta Oncol ,1989; 28(6):849-863.

Chinese Journal of Evidence-Based Medicine

How to Conduct A Systematic Review/Meta-analysis for Observational Studies

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