Application of Bispectral Index in Pediatric Anesthesia_West China Medical Journal

Authors：

CHEN Chunyan , LI Chao , CHENG Liming

Department of Anesthesiology, Kunming Children’s Hospital, Kunming, Yunnan 650034, P. R. China;

Corresponding author：

Keywords：

脑电双频指数; 麻醉; 丙泊酚; 小儿; 麻醉深度

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

目的　研究脑电双频指数（BIS）在小儿麻醉中的应用，为BIS在小儿临床麻醉上的广泛应用及提高小儿麻醉的安全性提供依据。方法　2011年1月－3月拟行腹部外科手术的患儿60例，男39例，女21例；年龄1～4岁，美国麻醉医师协会分级Ⅰ～Ⅱ级，随机分为两组，每组各30例。S组：七氟醚、瑞芬太尼和维库溴铵维持麻醉；P组：丙泊酚、瑞芬太尼和维库溴铵维持麻醉。采用BIS监测麻醉深度，将BIS控制在50 ± 5，记录麻醉诱导前到手术探查期间不同时点的血流动力学参数及苏醒、拔管时间。结果　手术过程中P组血压及心率明显低于麻醉前水平（P＜0.05）。S组苏醒迅速、完全，苏醒时间与P组比较差异有统计学意义（P＜0.05）。S组的血流动力学稳定性优于P组，苏醒时间、拔管时间相对较短。麻醉诱导前两组的BIS值均为97 ± 1，意识消失时的BIS值为71 ± 2。BIS值为50 ± 5时，结果显示手术过程中（T4、T5、T6、T7）两组的心率、血压都很平稳。结论　BIS作为小儿麻醉镇静深度的监测指标有临床意义。

Citation： CHEN Chunyan,LI Chao,CHENG Liming. Application of Bispectral Index in Pediatric Anesthesia. West China Medical Journal, 2012, 27(4): 552-554. doi: Copy

1.	李静洁. 脑电双频指数用于儿科麻醉深度监测[J]. 上海第二医科大学学报, 2003, 5(23): 470-472.
2.	庄心良. 现代麻醉学[M]. 北京: 人民卫生出版社, 2003: 481.
3.	Doi M, Gajraj RJ, Mantzaridis H, et al. Relationship between calculated blood concentration of propofol and electrophysiological variables during emergence from anaesthesia: comparison of bispectral index, spectral edge frequency, median frequency and auditory evoked potential index[J]. Br J Anaesth, 1997, 78(2): 180-184.
4.	韦天全. 小儿麻醉深度监测研究现状[J]. 广西医学, 2010, 4(32): 466-468.
5.	于布为. 麻醉深度监测进展[J]. 中国医疗器械信息, 2005, 11(6): 5-10.
6.	Powers KS, Nazarian EB, Tapyrik SA, et al. Bispectral index as a guide for titration of propofol during procedural sedation among children[J]. Pediatrics, 2005, 115(6): 1666-1674.
7.	Olson DM, Cheek DJ, Morgenlander JC. The impact of bispectral index monitoring on rates of propofol administration[J]. AACN Clin Issues, 2004, 15(1): 63-73.
8.	Levine DA, Platt SL. Novel monitoring techniques for use with procedural sedation[J]. Pediatrics, 2005, 17(3): 351-354.
9.	Ganesh A, Watcha MF. Bispectral index monitoring in pediatric anesthesia[J]. Anaesthesiology, 2004, 17 (3): 229-234.
10.	Sadhasivam S, Ganesh A, Robison A, et al. Validation of the bispectral index monitor for measuring the depth of sedation in children[J], Anesth Analg, 2006, 102(2): 383-388.
11.	Muñoz HR, León PJ, Fuentes RS, et al. Prospective evaluation of the time to peak effect of propofol to target the effect site in children[J]. Acta Anaesthesiol Scand, 2009, 53(7): 883-890.
12.	王培, 冀翔宇, 王世端, 等. 七氟醚与异丙酚麻醉BIS 为50时血流动力学参数变化[J]. 齐鲁医学杂志, 2010, 10(25): 424-427.
13.	曲良超, 肖实, 郭善亮, 等. 脑电双频指数反馈调控丙泊酚靶控输注在小儿先心病手术中的应用[J]. 临床麻醉学杂志, 2010, 5(26): 400-402.

1. 　李静洁. 脑电双频指数用于儿科麻醉深度监测[J]. 上海第二医科大学学报, 2003, 5(23): 470-472.
2. 　庄心良. 现代麻醉学[M]. 北京: 人民卫生出版社, 2003: 481.
3. 　Doi M, Gajraj RJ, Mantzaridis H, et al. Relationship between calculated blood concentration of propofol and electrophysiological variables during emergence from anaesthesia: comparison of bispectral index, spectral edge frequency, median frequency and auditory evoked potential index[J]. Br J Anaesth, 1997, 78(2): 180-184.
4. 　韦天全. 小儿麻醉深度监测研究现状[J]. 广西医学, 2010, 4(32): 466-468.
5. 　于布为. 麻醉深度监测进展[J]. 中国医疗器械信息, 2005, 11(6): 5-10.
6. 　Powers KS, Nazarian EB, Tapyrik SA, et al. Bispectral index as a guide for titration of propofol during procedural sedation among children[J]. Pediatrics, 2005, 115(6): 1666-1674.
7. 　Olson DM, Cheek DJ, Morgenlander JC. The impact of bispectral index monitoring on rates of propofol administration[J]. AACN Clin Issues, 2004, 15(1): 63-73.
8. 　Levine DA, Platt SL. Novel monitoring techniques for use with procedural sedation[J]. Pediatrics, 2005, 17(3): 351-354.
9. 　Ganesh A, Watcha MF. Bispectral index monitoring in pediatric anesthesia[J]. Anaesthesiology, 2004, 17 (3): 229-234.
10. 　Sadhasivam S, Ganesh A, Robison A, et al. Validation of the bispectral index monitor for measuring the depth of sedation in children[J], Anesth Analg, 2006, 102(2): 383-388.
11. 　Muñoz HR, León PJ, Fuentes RS, et al. Prospective evaluation of the time to peak effect of propofol to target the effect site in children[J]. Acta Anaesthesiol Scand, 2009, 53(7): 883-890.
12. 　王培, 冀翔宇, 王世端, 等. 七氟醚与异丙酚麻醉BIS 为50时血流动力学参数变化[J]. 齐鲁医学杂志, 2010, 10(25): 424-427.
13. 　曲良超, 肖实, 郭善亮, 等. 脑电双频指数反馈调控丙泊酚靶控输注在小儿先心病手术中的应用[J]. 临床麻醉学杂志, 2010, 5(26): 400-402.

West China Medical Journal

Application of Bispectral Index in Pediatric Anesthesia

Abstract Full text Figures/Tables Video References Cited by

Format

Content