【摘要】　目的　 评价经皮冠状动脉成形术（percutaneous coronary interventions，PCI）术后，穿刺股动脉应用Perclose ProGlide血管缝合器止血的安全性、可靠性及对常见并发症的防范。　方法　 2007年4月-2009年5月，收治217例经股动脉PCI术后患者，根据术后是否使用血管缝合器将患者随机分成血管缝合器组（105例）和对照组（经手法压迫止血112例）。观察记录两组患者下肢制动时间及血管并发症等。　结果　 血管缝合器组103例操作成功（98.1%），2例失败；对照组成功112例（100%）。两组成功率比较，差异无统计学意义（P gt;0.05）。血管缝合器组和对照组患者下肢制动时间分别为（4.1±1.2）和（25.0±3.1）h，两组比较，差异有统计学意义（P lt;0.01）。术后两组并发症发生率比较，差异无统计学意义（P gt;0.05）。　结论　 血管缝合器是一种安全、可靠的止血方法，可明显缩短制动时间，无明显的穿刺部位血管并发症，熟练操作可减少并发症的发生。
【Abstract】　Objective　 To evaluate the safety of Perclose ProGlide Suture-Mediated Closure System applied to femoral artery puncture site after percutaneous coronary interventions (PCI) and to explore the prevention of possible common complications.　Methods　 A total of 217 patients who underwent PCI from April 2007 to May 2009 were randomly divided into Perclose ProGlide group (105 patients, hemostasis by Perclose ProGlide Suture-Mediated Closure System) and control group (112 patients, hemostasis by compression). The Lower-limb braking time and the complications were recorded and analyzed.　Results　 The successful rate was 98.1% (103 patients) in Perclose ProGlide group, and 100% (112 patients) in the control group; the difference between the two groups was not significant (P gt;0.05). But there was a significant difference (P lt;0.01) in Lower-limb braking time between the two groups[(4.1±1.2) and (25±3.1) hours]. The post-operative complications between the two groups didn’t differ much.　Conclusions　 Perclose ProGlide Suture-Mediated Closure System is a safe,effective and simple method after percutaneous coronary intervention to achieve immediate hemastasis. Skillfully processing may reduce the vascular complications.

Citation： SHEN Hongmei,ZHANG Zaiwei,SHEN Hongshu. Clinical Application and the Prevention of Complications of Perclose ProGlide Suture-mediated Closure System after Percutaneous Coronary Intervention. West China Medical Journal, 2011, 26(2): 258-259. doi: Copy