精神科门诊5-羟色胺再摄取抑制剂抗抑郁药物用药状况分析_West China Medical Journal

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杨晓蓉 ¹ , 黄雪花 ² , 王艳 ¹

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Keywords：

门诊; 5-羟色胺再摄取抑制剂; 限定日剂量; 用药; 分析

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【摘要】　目的　分析5-羟色胺再摄取抑制剂抗抑郁药物门诊治疗用药状况。　方法　抽取2010年8月23－29日四川大学华西医院精神科门诊1周的处方，采用限定日剂量分析法，分析用药频度、用药费用及合理用药情况。　结果　 1周门诊量3 625例，其中焦虑抑郁性障碍1 518例（41.88%）；诊断抑郁症者最多，为926例（61.0%），其次为焦虑症273例（18.0%）、焦虑状态132例（8.7%）、强迫症93例（6.1%），其余患者分别诊断为惊恐障碍、轻度抑郁症、抑郁状态及抑郁症伴焦虑等。用药频度由高到低依次为舍曲林、帕罗西汀、氟西汀、氟伏沙明和西酞普兰。日治疗消费额度由高到低依次:舍曲林、帕罗西汀、西酞普兰、氟西汀和氟伏沙明。　结论　 5-羟色胺再摄取抑制剂抗抑郁药物的门诊用药符合临床合理用药规律，遵循循证医学证据用药。

Citation： 杨晓蓉,黄雪花,王艳. 精神科门诊5-羟色胺再摄取抑制剂抗抑郁药物用药状况分析. West China Medical Journal, 2011, 26(7): 1088-1089. doi: Copy

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1. 　刘顺发. 我国抑郁症患病情况的流行病学研究现状[J]. 医学文选, 2006, 25(4): 861-863.
2. 　Eaton WW, Kalaydjian A, Scharfstein DO, et al. Prevalence and incidence of depressive disorder:the Baltimore ECA follow-up, 1998-2004[J]. Acta Psychiatr Scand, 2007, 116(3): 182-188.
3. 　Sareen J, Cox BJ, Afifi TO, et al. Combat and peacekeeping operations in relation to prevalence of mental disorders and perceived need for mental health care: findings from a large representative sample of military personnel[J]. Arch Gen Psychiatry, 2007, 64(7): 843-852.
4. 　陈新谦, 金有豫, 汤光. 新编药物学[M]. 16版. 北京: 人民卫生出版社, 2007: 171-183.
5. 　Xie F, Tan CH, Li SC. Are they being used safely? A retrospective cross-sectional tertiary health care survey of selective serotonin reuptake inhibitors prescribing practice in Singapore[J]. Hum Psychopharmacol, 2005, 20(7): 459-465.
6. 　Madianos MG, Sarhan AL, Koukia E. Major depression across West Bank: A cross-sectional general population study[J]. Int J Soc Psychiatry, 2011, Mar 25. [Epub ahead of print].
7. 　Abraham G, Milev R, Stuart Lawson J.T3 augmentation of SSRI resistant depression[J]. J Affect Disord, 2006, 91(2-3): 211-215.

West China Medical Journal

精神科门诊5-羟色胺再摄取抑制剂抗抑郁药物用药状况分析

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