WANG Wanjuan , CHEN Yuping
  • The Department of Dermatology, the Second Affiliated Hospital, Medical School of Xi’an Jiaotong University;
银屑病; 生长抑素; 表皮生长因子
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【摘要】目的探讨生长抑素(somatostatin,SS)和表皮生长因子(epidermal growth factor,EGF)在银屑病治疗中的相互作用机制。方法选择2008年1月12月门诊和住院的寻常型银屑病患者68例,用放射免疫法检测正常组织和各期银屑病皮损中SS和EGF的表达。结果进行期银屑病皮损中EGF明显高于静止期、恢复期皮损和正常皮肤(P＜001);各期银屑病皮损与正常皮肤中SS差异无统计学意义(P＜005)。结论SS可能是通过抑制EGF而在银屑病的治疗中起关键作用。

Citation： WANG Wanjuan,CHEN Yuping. Detection of Somatostatin and Epidermal Growth Factor in Psoriatic Lesions. West China Medical Journal, 2010, 25(2): 326-. doi: Copy