方法 回顾分析从2007年1月-2009年12月收治的12例成人Still病患者的临床资料，观察其临床特点。 结果 12例患者体温均≥39.0℃，有一过性皮疹、关节疼痛，周围血常规白细胞总数、中性粒细胞增高（白细胞≥15.0×109/L、中性粒细胞≥80%），血沉、C-反应蛋白、血清铁蛋白增高，骨髓涂片为增生性骨髓像，其次有咽痛，肝、脾、淋巴结肿大等临床表现。糖皮质激素是治疗的主要措施。 结论 成人Still病临床表现复杂多样，实验室检查缺乏特异性，血清铁蛋白检测值的明显增高有助于诊断。患者经糖皮质激素治疗后预后效好。
【Abstract】 Objective To observe the clinical characteristics of adult onset Still’s disease and enhance the awareness of the disease. Methods The clinical data of 12 patients with Still’s disease from January 2007 to December 2009 were retrospective analyzed. The clinical characteristics of the disease were observed. Results Twelve patients had high fever (body temperature≥39.0℃), evanescent eruption, arthralgia, increase of leucocyte and neutrophilic granulocyte (leucocyte≥15.0×109/L, neutrophilic granulocyte≥80%), blood sedimentation, and C-reactive protein, increase of serum ferritin, bone marrow smear being hyperplasticmyelogram, as well as the tumefaction of angina, liver, spleen, and lymphaden. Glucocorticoid was the main measure of the treatment. Conclusions Clinical presentation of adult Still’s disease is various with involvement of many systems with lack of specificity of the lab inspection. Obvious increase of detected value of serum ferritin attributes greatly to the diagnosis. The prognosis of the patients who have undergone glucocorticoid treatment is very good.
Citation： LI Xianyong,XIA Gang,SU Zunwei. Clinical Features of Adult Still’s Disease. West China Medical Journal, 2010, 25(10): 1805-1807. doi: Copy