LIU Hanfang , CHENG JunJie , CHEN Fei , ZHANG Yanqing
  • Department of Examination, Nuclear Industry 215 Hospital, Shanxi Medical College, Xianyang, Shanxi 712000,P.R.China;
无症状人群; 高尿酸血症; 高甘油三酯血症; 相关性
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【摘要】　目的　 探讨无症状人群高尿酸血症与高甘油三酯血症的相关性，为临床疾病的预防和治疗提供实验基础研究。　方法　 回顾分析2008年5月-2009年5月门诊体检中200名无临床症状高血尿酸者（A组）的血脂检查情况，并与同期200例血尿酸正常者（B组）的血脂检查情况进行比较分析。A组：男121例，女79例；年龄20～60岁，平均43岁。男性患者血尿酸 gt;420 mmol/L，女性患者 gt;360 mmol/L。 B组：男115例，女85例；年龄20～60岁，平均41岁。男性患者血尿酸为99～420 mmol /L，女性患者为99～360 mmol/L。两组性别和年龄差异无统计学意义（P gt;0.05）。　结果　 A组甘油三酯、总胆固醇、低密度脂蛋白、高密度脂蛋白分别为（3.09±0.98）、（4.05±1.07）、（3.38±0.98）、（1.30±0.51）mmol /L；B组为（1.65±0.86）、（3.99±0.99）、（2.97±0.89）、（1.41±0.66）mmol /L。 A组甘油三酯较B组比较，差异有统计学意义（P lt;0.01）；总胆固醇、低密度脂蛋白、高密度脂蛋白比较，差异无统计学意义（P gt;0.05）。经相关性分析，A组血尿酸与甘油三酯呈正相关（r=0.69， P lt;0.01）。　结论　 血尿酸代谢与甘油三酯代谢之间有一定的联系。
【Abstract】　Objective　 To explore the correlation between hyperuricemia and hypertriglyceridemia in asymptomatic people to provide the basic information for clinical prevention and treatment.　Methods　 The blood lipid (TG, TC, LDL, and HDL) levels in 200 asymptomatic individuals with high uric acid (A group) and 200 sex-and age-matched ones with normal serum uric acid (B group) were examined and the results of the two groups were compared.　Results　 The concentration of triacylglycerol, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol were (3.09±0.98), (4.05±1.07), (3.38±0.98), and (1.30±0.51) mmol/L, respectively in group A; and were (1.65±0.86), (3.99±0.99), (2.97±0.89), and (1.41±0.66) mmol /L, respectively in group B. The concentration of TG in group A was obvious higher than that in group B (P lt;0.01). However, the differences of their total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol were not significant (P gt;0.05). The increase of TG was obvious compared with TC(P lt;0.01), LDL (P lt;0.01), and HDL (P lt;0.01) in group A; while the comparisons in group B were not significant (P gt;0.05).　Conclusion　 Uric acid metabolism correlates with triacylglycerol metabolism.

Citation： LIU Hanfang,CHENG JunJie,CHEN Fei,ZHANG Yanqing. Correlation between Hyperuricemia and Hypertriglyceridemia in Asymptomatic People. West China Medical Journal, 2010, 25(11): 2058-2059. doi: Copy