目的:研究外伤性脑梗死患者血小板P选择素动态变化的临床意义。方法:用流式细胞仪测定42例外伤性脑梗死患者,50例无脑梗死外伤患者及40例正常对照者外周血血小板P选择素。结果:急性期(1周内)外伤性脑梗死患者P选择素明显高于无梗死脑外伤患者和健康对照组(P lt;0.01)。14 d时,外伤性脑梗死患者血小板P选择素表达,与无梗死脑外伤患者和健康对照组无显著差异(P gt;0.005)。结论:P选择素参与外伤性脑梗死的病理过程,测定它们有利于外伤性脑梗死的早期诊治,改善预后。
Citation:
ZENG Lingchun,LI Zhongping. Clinical Significance of Dynamic Detection of Plasma P-selectin in the Patients with Traumatic Cerebral Infarction. West China Medical Journal, 2009, 24(2): 267-268. doi:
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- 2. Marquordt L,Ruf A,Mansmann U,et al.Course of platete activation markers after ischemic stroke[J].Stroke,2002,33(11):2570-2574..
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