目的:探讨喉巨细胞瘤的临床病理学特征及诊断、鉴别诊断要点.方法:报道1例喉巨细胞瘤,结合文献对其临床表现、影像学情况、病理形态学特点及鉴别诊断进行分析和探讨。结果:巨细胞瘤好发于长骨末端,约5%累及扁骨,不足5%的病例累及手足部的短管状骨,2%发生于头颈部。喉巨细胞瘤极罕见,发病平均年龄为42.4岁,男性多见。本例34岁,男性,左侧声门下3 cm×2 cm×2 cm肿块。镜下表现为圆形、卵圆形单核细胞及均匀分布其间的破骨细胞样巨细胞混合组成。结论:喉巨细胞瘤罕见,临床易误诊为恶性肿瘤,其病理学检查有特征性形态改变,结合影像学改变,可以确诊。
Citation:
WANG Anqun,XIE Gang,YANG Yonghong,et al.. Clinicopathological Analysis of Larynx Giant Cell Tumor. West China Medical Journal, 2009, 24(2): 425-428. doi:
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Christopher D.M.Fletcher,K.Krishnan Unni,Fredrik Mertens.世界卫生组织肿瘤分类及诊断标准系列:软组织与骨肿瘤病理学和遗传学[M].北京:人民卫生出版社,2006:368-370..
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- 1. Christopher D.M.Fletcher,K.Krishnan Unni,Fredrik Mertens.世界卫生组织肿瘤分类及诊断标准系列:软组织与骨肿瘤病理学和遗传学[M].北京:人民卫生出版社,2006:368-370..
- 2. Wieneke JA,Gannon FH,Heffner DK,et al.Giant cell tumor of the larynx:A clinicopathologic series of eight cases and a Review of the literature[J].Mod Pathol,2001,14:1209-1215..
- 3. Hinni ML.Giant cell tumor of the larynx[J].Ann otol Rhinol laryngol,2000,109:63-66..
- 4. Werner JA,Harms D,Beigel A.Giant cell tumor of the larynx:case report and review of the literature[J].Head Neck,1997,19:153-157..
- 5. Devaney KO,Ferlito A,Rinaldo A.Giant cell tumor of the larynx[J].Annu Otol Rhinol Laryngol,1998,107:729-732..
- 6. 许元腾,肖文惠,杨劲松,等.喉巨细胞瘤1例[J].临床耳鼻咽喉科杂志,2003,3:166.