Prognosis and FollowUp Information Analysis of 499 Cases of Endometrial Carcinoma_West China Medical Journal

Authors：

WU Xiuli , HE Ying , YANG Kaixuan.

Department of Pathology, West China Second Hospital, Sichuan University, Chengdu 610041,China;

Corresponding author：

Keywords：

子宫内膜癌; 随访; 预后

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

目的:总结分析子宫内膜癌临床特点、治疗方法的疗效及与各预后高危因素之间的关系，以提高临床诊疗水平。方法:回顾性分析我院1998年1月～2005年12月收治住院的子宫内膜癌患者499例的临床病理资料，总结患者的一般情况、临床特点并进行随访，分析内膜癌高危因素对预后的影响。采用寿命表法计算患者生存率，Wilcoxon (Gehan) 比分法及Cox比例风险模型分析预后因素。结果:(1) 手术－病理分期I、Ⅱ、Ⅲ期患者5年生存率分别为94%、100％、75.3％，IV期患者1年生存率57.1%、2年生存率11.4％。(2) 单因素分析显示：病理类型、手术－病理分期、组织学分级、肌层浸润深度、淋巴结转移和是否行淋巴结切除术是影响预后的高危因素。（3）多因素分析显示：病理类型、手术－病理分期、组织学分级和肌层浸润深度是影响患者预后的独立危险因素。结论:(1) 对具有高危因素的患者，如特殊病理类型、手术－病理分期期别晚、组织学分级为G3和深肌层浸润，应辅以术后治疗以提高生存率。(2)分期越晚，生存率越低（P lt;0.05）。

Citation： WU Xiuli,HE Ying,YANG Kaixuan.. Prognosis and FollowUp Information Analysis of 499 Cases of Endometrial Carcinoma. West China Medical Journal, 2009, 24(6): 1403-1407. doi: Copy

1.	曹泽毅主编. 中华妇产科学[M].北京: 人民卫生出版社, 第一版.1999: 1844-1845..
2.	FIGO ( International Federation of Gynecology and Obstetrics ) annual report on the results of treatment in gynecological cancer[J]. Int J Gynaecol Obstet, 2003, 83 Suppl 1: ixxxii, 1-229..
3.	JAIME PART. Prognostic parameters of endometrial carcinoma[J]. Human pathology,2004, 35 (6) : 649-662..
4.	彭芝兰, 刘兴会, 张家文,等. 子宫内膜癌290例临床分析与手术病理分期的比较[J]. 中华妇产科杂志,1997, 32（10）: 597-600..
5.	ELTABBAKH G, MOORE A. Survival of women surgical stage Ⅱ endometrial cancer[J]. Gynecol Oncol, 1999, 74: 80-85..
6.	BORONOW RC. Surgical staging of endometrial cancer: Evolution, evaluation, and responsible challenge. A personal perspective[J]. Gynecol Oncol, 1997, 66: 179-189..
7.	CREASMAN WT, DISAIA PJ, BLESSING J, et al. Prognostic significance of peritoneal cytology in patients with endometrial cancer and preliminary data concerning therapy with intraperitoneal radioparmaceuticals[J]. Am J Obstet Gynecol, 1981,141:921-929..
8.	LURAIN JR, RUMSEY NK, SCHINK JC, et al. Prognostic significance of positive peritoneal cytology in clinical stage I adenocarcinoma of endometrium[J]. Obstet Gynecol, 1989,74:175179..
9.	KADAR N, HOMESLEY HD, MALFETANO JH. Positive peritoneal cytology is an adverse factor in endometrial carcinoma only if there is other evidence of extrauterine disease[J]. Gynecol Onkol, 1992,46:145-149.
10.	KILGORE LC, PARTRIDGE EE, ALVAREZ RD, et al. Adenocarcinoma of the endometrium: survival comparisons of patients with and without pelvic node sampling[J]. Gynecol Onkol, 1995, 56:29-33..
11.	MOHAN DS, SAMUEL MA, SELIM MA, et al. Longterm outcomes of therapeutic pelvic lymphadenectomy for stage I adenocarcinoma[J]. Gynecol Onkol, 1998, 70: 165-171..
12.	ALESSANDRO D SANTIN , STEFANIA BELLONE , TIMOTHY J O’BRIEN, et al. Current treatment options for endometrial cancer. Expert Rev[J]. Anticancer Ther, 2004,4 (4) :679689..
13.	曹泽毅. 妇科恶性肿瘤治疗中对淋巴处理的商榷[J]. 中华妇产科学,2004, 39（2）: 135-147..

1. 曹泽毅主编. 中华妇产科学[M].北京: 人民卫生出版社, 第一版.1999: 1844-1845..
2. FIGO ( International Federation of Gynecology and Obstetrics ) annual report on the results of treatment in gynecological cancer[J]. Int J Gynaecol Obstet, 2003, 83 Suppl 1: ixxxii, 1-229..
3. JAIME PART. Prognostic parameters of endometrial carcinoma[J]. Human pathology,2004, 35 (6) : 649-662..
4. 彭芝兰, 刘兴会, 张家文,等. 子宫内膜癌290例临床分析与手术病理分期的比较[J]. 中华妇产科杂志,1997, 32（10）: 597-600..
5. ELTABBAKH G, MOORE A. Survival of women surgical stage Ⅱ endometrial cancer[J]. Gynecol Oncol, 1999, 74: 80-85..
6. BORONOW RC. Surgical staging of endometrial cancer: Evolution, evaluation, and responsible challenge. A personal perspective[J]. Gynecol Oncol, 1997, 66: 179-189..
7. CREASMAN WT, DISAIA PJ, BLESSING J, et al. Prognostic significance of peritoneal cytology in patients with endometrial cancer and preliminary data concerning therapy with intraperitoneal radioparmaceuticals[J]. Am J Obstet Gynecol, 1981,141:921-929..
8. LURAIN JR, RUMSEY NK, SCHINK JC, et al. Prognostic significance of positive peritoneal cytology in clinical stage I adenocarcinoma of endometrium[J]. Obstet Gynecol, 1989,74:175179..
9. KADAR N, HOMESLEY HD, MALFETANO JH. Positive peritoneal cytology is an adverse factor in endometrial carcinoma only if there is other evidence of extrauterine disease[J]. Gynecol Onkol, 1992,46:145-149.
10. KILGORE LC, PARTRIDGE EE, ALVAREZ RD, et al. Adenocarcinoma of the endometrium: survival comparisons of patients with and without pelvic node sampling[J]. Gynecol Onkol, 1995, 56:29-33..
11. MOHAN DS, SAMUEL MA, SELIM MA, et al. Longterm outcomes of therapeutic pelvic lymphadenectomy for stage I adenocarcinoma[J]. Gynecol Onkol, 1998, 70: 165-171..
12. ALESSANDRO D SANTIN , STEFANIA BELLONE , TIMOTHY J O’BRIEN, et al. Current treatment options for endometrial cancer. Expert Rev[J]. Anticancer Ther, 2004,4 (4) :679689..
13. 曹泽毅. 妇科恶性肿瘤治疗中对淋巴处理的商榷[J]. 中华妇产科学,2004, 39（2）: 135-147..

West China Medical Journal

Prognosis and FollowUp Information Analysis of 499 Cases of Endometrial Carcinoma

Abstract Full text Figures/Tables Video References Cited by

Format

Content