Clincal Study of Noninvasive Ventilation for Respiratory Failure Resulting from Acute Exacerbations of Chronic Obstructive Pulmonary Disease_West China Medical Journal

Authors：

WAN Xiaobing , CHENG Yujie , LU Haiying , et al.

Department of Respiratory Disease, Sichuan Provence No.4 People’s Hospital, Chengdu 610016,China;

Corresponding author：

Keywords：

双水平气道正压通气; 慢性阻塞性肺疾病; Ⅱ型呼吸衰竭

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目的:探讨鼻(面)罩无创双水平气道正压通气(BiPAP)在慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的治疗作用。方法:入选病例60例,分为常规治疗组28例,采用常规治疗;呼吸机治疗组32例,在常规资料基础上加用BiPAP无创呼吸机治疗,两组患者心率,呼吸频率,血气分析比较。结果:呼吸机治疗组患者心率,呼吸频率,血气分析的改善优于常规治疗组,差异有统计学意义(P lt; 0.05)。结论:无创双水平气道正压机械通气辅助治疗COPD合并Ⅱ型呼吸衰竭具有肯定的疗效,能更快地缓解患者的临床症状;提高PaO2,SaO2和降低PaCO2;能更好地促进病情的恢复,减少住院时间。

Citation： WAN Xiaobing,CHENG Yujie,LU Haiying,et al.. Clincal Study of Noninvasive Ventilation for Respiratory Failure Resulting from Acute Exacerbations of Chronic Obstructive Pulmonary Disease. West China Medical Journal, 2009, 24(6): 1431-1433. doi: Copy

1.	朱蕾,钮善福,张书平,等.经面罩机械通气治疗慢性阻塞性肺疾病呼吸衰竭患者的回顾性分析[J].中华结核和呼吸杂志,2003,26(7):407-410.
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3.	CONTIG, ANTONELLIM, NAVALESIP, et al. Noninvasive vs. conventional mechanical ventilation in patients with chronic obstructive pulmonary disease after failure of medical treatment in the ward a randomized trial[J].Intensive Care Med,2002,28(12):1701-1707.
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5.	曹志新,王辰.无创机械通气的应用范围及指征[J]. 中华结核和呼吸杂志,2002,25(3):136-137.
6.	Pauwels RA, Buist AS, Calverlry PMA, et al.NHLBI/WHO global initiative for chronic obstructive lung disease (GOLD)workshop summary.Global strategy for the diagnosis,management,and prevention of chronic obstructive lung disease[J]. Am J Respir Crit Care Med, 2001,163(5):1257-1276.
7.	王宋平,李国平,王荣丽,等.无创通气治疗慢性阻塞性肺疾病急性呼吸衰竭的临床研究[J].中国呼吸与危重监护杂志,2002,1(4):233-235.

1. 朱蕾,钮善福,张书平,等.经面罩机械通气治疗慢性阻塞性肺疾病呼吸衰竭患者的回顾性分析[J].中华结核和呼吸杂志,2003,26(7):407-410.
2. 中华医学会呼吸病分会.慢性阻塞性肺疾病诊治指南[J]. 中华结核和呼吸杂志,2002,25(8):453-460.
3. CONTIG, ANTONELLIM, NAVALESIP, et al. Noninvasive vs. conventional mechanical ventilation in patients with chronic obstructive pulmonary disease after failure of medical treatment in the ward a randomized trial[J].Intensive Care Med,2002,28(12):1701-1707.
4. 王辰,张洪玉.改进慢性阻塞性肺疾病合并呼吸衰竭的机械通气策略[J].中华内科杂志,2000,39(6):369.
5. 曹志新,王辰.无创机械通气的应用范围及指征[J]. 中华结核和呼吸杂志,2002,25(3):136-137.
6. Pauwels RA, Buist AS, Calverlry PMA, et al.NHLBI/WHO global initiative for chronic obstructive lung disease (GOLD)workshop summary.Global strategy for the diagnosis,management,and prevention of chronic obstructive lung disease[J]. Am J Respir Crit Care Med, 2001,163(5):1257-1276.
7. 王宋平,李国平,王荣丽,等.无创通气治疗慢性阻塞性肺疾病急性呼吸衰竭的临床研究[J].中国呼吸与危重监护杂志,2002,1(4):233-235.

West China Medical Journal

Clincal Study of Noninvasive Ventilation for Respiratory Failure Resulting from Acute Exacerbations of Chronic Obstructive Pulmonary Disease

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