Analysis of the Related Factors of Peripheral Arterial Disease in Lower Limbs of Type 2 Diabetes Patients_West China Medical Journal

Authors：

SHEN Jing ¹ , LIU Changping. ²

1Chengdu Geriatric Hospital of Sichuan Province, Chengdu 611130; 2People’s Hospital of Pengzhou of Sichuan Province, Pengzhou Sichuan 611930, China;

Corresponding author：

Keywords：

2型糖尿病; 踝肱指数; 下肢动脉病变

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目的:通过踝肱指数 (ABI)检查,探讨2型糖尿病患者下肢动脉病变 (PAD)的患病率及其影响因素。方法:采用血管多普勒诊断仪对120名 2型糖尿病患者进行 ABI测定,ABI lt;0. 9为 PAD组,ABI≥0. 9为非PAD组,分析比较2组患者的代谢参数。结果:检出ABI lt;0.9者31例,占总例数的25. 8%。与非 PAD组比较, PAD组患者年龄大、病程长,餐后2h血糖、SBP 、DBP、TG、LDL  C、HbA1c均明显升高,有显著性差异 (P lt;0.05)。结论:ABI在诊断2型糖尿病下肢动脉病变中具有重要意义;年龄、病程、高 LDLC、高TG、高血糖、高血压为下肢动脉病变的主要危险因素。

Citation： SHEN Jing,LIU Changping.. Analysis of the Related Factors of Peripheral Arterial Disease in Lower Limbs of Type 2 Diabetes Patients. West China Medical Journal, 2009, 24(6): 1458-1460. doi: Copy

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5.	潘长玉,高妍,袁申元,等.2型糖尿病下肢血管病变发生率及相关因素调查[J].中国糖尿病杂志,2001,9(6):323-326.
6.	Aerican Diabetes Association.Peripheral arterial disease in people with diabetes [J].Diabetes Care,2003,26(12): 3333-3341.
7.	ARONOW WS, AHN C, WEISS MB, et al. Relation of increased hemoglobin A 1c levels to severity of peripheral arterial disease in patients with diabetes mellitus[J].Am J Cardiol,2007,99:1468-1469.
8.	王爱红,许樟荣,王玉珍,等踝肱指数诊断糖尿病下肢动脉病变的临床意义[J].中国糖尿病杂志, 2006,14(2):105-107.
9.	HOOI JD, KESTER AD, STOFERS HE, et al. A symptomatic peripheral arterial occlusive disease predicted cardiovascular morbidity and mortality in a 7year followup study[J]. J Clin Epidemiol,2004,25:122.
10.	HOY W, LIGHT A, MEGILL D. Cardiovascular disease in Navajo Indians with type 2 diabetes[J ]. Publie Health Rep,1995,110 (1):87-94.
11.	许樟荣,我国糖尿病足研究的现状与思考[J].中国糖尿病杂志，2007,15(11):641.

1.
2. DOLAN NC LIU K,CRIQUI M. Peripher alartery disease diabetes and reduced lowe rextremity functioning [J]. Diabetes Care,2002,25:113-120.
3. BENDERMACHER BL, TEIJINK JA,WILLIGENDAEL EM, et al. A clinical prediction model for the presence of peripheral arterial diseasethe benefit of screening individuals before initiation of measurement of the ankle brachial index: an observational study[J]. VascMed,2007,12:5-11.
4. HIATT WR. Medical treatment of peripheral arterial disease and claudication [J].N Engl J Med, 2001,344(21): 1608-1621.
5. 潘长玉,高妍,袁申元,等.2型糖尿病下肢血管病变发生率及相关因素调查[J].中国糖尿病杂志,2001,9(6):323-326.
6. Aerican Diabetes Association.Peripheral arterial disease in people with diabetes [J].Diabetes Care,2003,26(12): 3333-3341.
7. ARONOW WS, AHN C, WEISS MB, et al. Relation of increased hemoglobin A 1c levels to severity of peripheral arterial disease in patients with diabetes mellitus[J].Am J Cardiol,2007,99:1468-1469.
8. 王爱红,许樟荣,王玉珍,等踝肱指数诊断糖尿病下肢动脉病变的临床意义[J].中国糖尿病杂志, 2006,14(2):105-107.
9. HOOI JD, KESTER AD, STOFERS HE, et al. A symptomatic peripheral arterial occlusive disease predicted cardiovascular morbidity and mortality in a 7year followup study[J]. J Clin Epidemiol,2004,25:122.
10. HOY W, LIGHT A, MEGILL D. Cardiovascular disease in Navajo Indians with type 2 diabetes[J ]. Publie Health Rep,1995,110 (1):87-94.
11. 许樟荣,我国糖尿病足研究的现状与思考[J].中国糖尿病杂志，2007,15(11):641.

West China Medical Journal

Analysis of the Related Factors of Peripheral Arterial Disease in Lower Limbs of Type 2 Diabetes Patients

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