目的:探讨立体定向脑病变活检术的手术技巧及影响因素。方法:总结20例立体定向活检病例,其中多发病灶者4例,单发病灶者16例。使用CT、MRI扫描、立体定向仪及手术计划系统精确定位靶点、制定合适的活检轨迹。使用Backlund和Sedan活检针取材,脑浅表病灶使用立体定向环钻开颅全切。术中冰冻活检,术后石蜡包埋病理检查和免疫组化检查。结果:19例获明确的病理诊断,活检阳性率95%。其中,9例脑胶质瘤,3例海绵状血管瘤、2例脑转移瘤,3例非特异性炎性肉芽肿,1例结核性肉芽肿,1例脑弓形虫病。结论:立体定向脑病变活检术是神经外科十分重要的安全的诊治手段。
Citation:
CAI Xiaodong,GAO Yongzhong,LI Weiping,et al. Stereotactic Biopsy of Brain Lesions. West China Medical Journal, 2009, 24(7): 1816-1818. doi:
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LEE T, KENNY BG, HITCHCOCK ER, et al. Supratentorial Masses: Stereoatactic or freehand biopsy[J]. Br J Neurosurg,1991,5:331-338..
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ChANDRASOMA P T, SMITH M M, APAZZO M L J. Stereotactic biopsy in the diagnosis of brain. Masses: comparison of results of biopsy and resected Surgical specimen[J].Neurosurgery,1989,24:160-165..
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SAM P, JAVEDAN B A, TAMARGO R J. Diagnosis yield of brain biopsy in neurodegenerative disorders[J]. Newrosurgery.1997,41: 823-830..
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傅光明,牛朝诗.立体定向和功能神经外科学[M].第1版.合肥:安徽科学技术出版社,2004:693..
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- 1. LEE T, KENNY BG, HITCHCOCK ER, et al. Supratentorial Masses: Stereoatactic or freehand biopsy[J]. Br J Neurosurg,1991,5:331-338..
- 2. ChANDRASOMA P T, SMITH M M, APAZZO M L J. Stereotactic biopsy in the diagnosis of brain. Masses: comparison of results of biopsy and resected Surgical specimen[J].Neurosurgery,1989,24:160-165..
- 3. SAM P, JAVEDAN B A, TAMARGO R J. Diagnosis yield of brain biopsy in neurodegenerative disorders[J]. Newrosurgery.1997,41: 823-830..
- 4. 傅光明,牛朝诗.立体定向和功能神经外科学[M].第1版.合肥:安徽科学技术出版社,2004:693..