目的:探讨胸膜活检对胸腔积液病因诊断的价值。方法:对127例胸腔积液患者行首次胸膜活检术。结果:127例患者获取胸膜组织125例, 穿刺成功率98.4%,经病理检查有41例为正常胸膜组织,特异性病理诊断84例,病理诊断阳性率(67.2%)。恶性胸腔积液胸膜活检阳性38例(45.2%),结核性胸腔积液胸膜活检阳性31例(36.9%),非特异性炎15例(17.9%)。38例恶性肿瘤经免疫组织化学和特殊染色分类,腺癌27例,小细胞肺癌2例,鳞癌2例,恶性间皮瘤2例,转移癌3例,淋巴瘤1例,未分化癌1例。发生并发症者4例(3.1%),全部为气胸,肺压缩均小于15%,未做特殊处理数日后自行吸收。结论:胸膜活检是一项安全、简单、有效的胸膜疾病的重要的内科确诊手段。
Citation：
CHEN Lipin,YANG Xiaohong,WU Chao. The Value of Pleural Biopsy in the Etiological Diagnosis of Pleural Effussion. West China Medical Journal, 2009, 24(8): 2018-2020. doi:
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- 1. 朱元珏,陈文彬.呼吸病学[M].北京:人民卫生出版社,2002:487-489,1279-1282.
- 2. SOKOLOWSKI J W, URGHER L W, ONES F L, et al. Guidelines for thoracentesis and needle biopsy of the pleural[J].Am Rev Respir Dis,1989,140(1):257-258.
- 3. BAUMANNMH. CLOSED LEURAL BIOPSY: NOT DEAD YET.[J] Chest,2006,129 (6):1398-1400.
- 4. 曹雪如.胸膜活检诊断不明原因胸腔积液的临床分析[J].临床肺科杂志.2006.3(11):292.
- 5. CHAKRABARTI B, RYLAND I, SHEARD J, et al. The role of Abrams percutaneous pleural biopsy in the investigation of exudative pleural effusions[J]. Chest,2006, 129 (6):1549-1555.
- 6. 解郑良, 刘跃建,黄纪贵. 胸膜活检对胸腔积液病因诊断的临床价值[J].华西医学,2008, 23(1):40.
- 7. 张素娟,潘顺权,刘皓.胸膜活检在胸膜疾病诊断中的地位和安全性评估[J].中华全科医师杂志,2003,2(6):358-360.
