Radiological Analysis of the Hand in 60 Patients with Rheumatoid Arthritis_West China Medical Journal

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the Department of Rheumatology, West China Hospital, Sichuan University, Chengdu 610041, China;

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Keywords：

类风湿关节炎; X线检查; 类风湿因子; C反应蛋白

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目的:探讨类风湿关节炎(RA)患者手部X线的表现与临床指标关系。方法:对60例临床资料完整的RA病例行双手正侧位X线检查,分为符合类风湿关节炎X线I期表现的32例(第1组),符合类风湿关节炎Ⅱ期及以上表现的患者28例(第2组),分别统计类风湿关节炎患者的临床指标类风湿因子(RF)、红细胞沉降率(ESR)、C反应蛋白(CRP)和关节肿胀个数进行两组比较,以及对影像学Sharp评分和临床各指标相关性进行评价分析。结果:两组RA患者的RF、ESR、CRP和关节肿胀数第2组明显高于第1组,两组差异均具有显著性(P lt;0.05),Sharp评分与ESR、CRP、RF、关节肿胀数均有相关性,它们的r值、P值分别为r=0.414,P=0001;r=0.481,P=0.000;r=0.333,P=0.009;r=0.261,P=0.044。结论:类风湿关节炎Ⅱ期及以上表现的患者RF、ESR、CRP和关节肿胀数明显高于类风湿关节炎X线Ⅰ期表现的患者,Sharp评分和RF、ESR、CRP和关节肿胀数有一定相关性,说明RF、ESR、CRP和关节肿胀数对类风湿关节炎的预后有预测作用。

Citation： ZHAO Zhenyi,YANG Nanping,LIU Xiaoxiao,et al. Radiological Analysis of the Hand in 60 Patients with Rheumatoid Arthritis. West China Medical Journal, 2009, 24(8): 2076-2077. doi: Copy

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1. 中华风湿病学会.类风湿关节炎的诊治指南[J].中华风湿病杂志,2003,7(4): 252-254.
2. 罗昔波,唐爱国.类风湿性关节炎自身抗体研究进展[J].实用预防医学,2007,3:168.
3. JANSEN L M A, VAN DER HAORSTBRUINSMA I E, VAN SCHAARDENBURG D, et al. Predictors of radiographic joint damagein patients with early rheumatoid arthritis[J ]. Ann Rheum Dis,2001,60(8):924.
4. MEYER O, LABARRE C, DOUGADOS M, et al. Anticitrullinated protein peptide antibody assays in early rheumatoid arthritis for predicting five years radiographic damage[J ]. Ann Rheum Dis,2003,62(2):120-126.
5. 杨梅.影像学检查在类风湿关节炎诊断中的应用[J].安徽中医学院学报,2006,25(4):62-64.
6. 叶日乔.类风湿性关节炎早期血清和影像学诊断的研究概述[J].辽宁中医学院学报,2005,5:83.

West China Medical Journal

Radiological Analysis of the Hand in 60 Patients with Rheumatoid Arthritis

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