Impact of Pulse Pressure on Left Ventricular Hypertrophy in Senile Patients with Essential Hypertension_West China Medical Journal

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Department of Cardiology,The Third People’s Hospital of Chengdu City,Chengdu 610031,China;

Corresponding author：

Keywords：

原发性高血压; 脉压; 左心室肥厚

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目的:探讨24 h平均脉压(PP)对高血压病患者左心室肥厚(LVH)的影响。方法:入选原发性高血压病患者136 例,进行24 h 动态血压监测和超声心动图检查。根据24 h 平均脉压水平各分为3组进行比较。结果:24 h平均脉压与年龄、左心室重量指数、动脉僵硬度指数有显著的相关性。结论:脉压升高是老年高血压病患者左心室肥厚的重要危险因素。

Citation： WU Jing,CAI Lin,WANG Wei,et al.. Impact of Pulse Pressure on Left Ventricular Hypertrophy in Senile Patients with Essential Hypertension. West China Medical Journal, 2009, 24(8): 2125-2127. doi: Copy

1.	ASMAR R. Pulse pressure and aortic pulse wave are markers of cardiovascular risk in hypertensive populations[J]. Am J Hypertens,2001,14 (2):91-97.
2.	KHATTAR. Value of ambulatory imtra arterial blood pressure monitoring in the long term prediction of left ventricular hypertophy and carotid atherosclerosis in essential hypertension[J]. J Hum Hypertens,1999,13 (2):111 – 116.
3.	VERDECCHIA P,SCHILLACI G,BORGIONI C,et al. Ambulartory pulse pressure: a potent predicition of total cardio vascular risk in hypertension[J]. Hypertension,1998,32 (6):983- 988.
4.	刘力生.中国高血压防治指南[M]. 北京:人民卫生出版社,2005: 14.
5.	OTELIO SR, NICO W, GERARD CB, et al. Reliability of stroke volume to pulse pressure ratio for estimating and detecting changes in arterial compliance[J].J Hypertens,1986,4(Suppl 5):S293-S296.
6.	ALDERMAN MH. A new medel of risk:implication of increasing pulse pressure and systolic blood pressure on cardiovascular disease[J]. J Hypertension,1999,17 (Suppl5):25-28.
7.	BOUTOUYRIE P,BUSSY C,LACOLLY P,et al.Association between local pulse pressure,mean blood pressure and large artiry remodeling[J]. Circulation,1999,100 (13):1387.
8.	KHATTAR RS,ACHARYA DU,KINSEY C,et al. Congitudinal association of ambulatory pluse pressure with left ventricular mass and vascular hypertrouy in essential hypertension[J]. J Hypertens,1997,15 (7):707-743.
9.	FRANKLIN SS, GUSTIN W4T H, WONG ND, et al. Hemodynamic patterns of agerelated changes in blood pressure. The Framingham study[J]. Circulation,1997,96:308-315.
10.	KHATTAR. Value of ambulatory imtra arterial blood pressure monitoring in the long term prediction of left ventricular hypertophy and carotid atherosclerosis in essential hypertension[J]. J Hum Hypertens,1999,13 (2):111-116.
11.	O’ROURKE MF, HAYWARD CS, LEHMAN ED, et al. Arterial stiffness. In:Oparil S,Weber MA, eds, Hypertension:a companion to Brenner & Rector’s Kidney[J]. Sauders,2000:134-151.
12.	GELENTANO A, PALMIERI V, PALMA EN, et al.. Relations of pulse pressure and other components of blood pressure to preclinical echocardiographic abnormalities[J].J Hypertens,2002,20: 531-537.
13.	JOKINIITTY JM, TUOMISTO MT, MAJAHALME SK, et al.. Pulse pressure responses to psychological tasks improve the prediction of left ventricular mass: 10 years of followup[J].J Hypertens,2003,21:789-795.
14.	MULE G, NARDI E, ANDRONICO G, et al. Pul satile and steady 24 h blood pressure components as determinants of left ventricular mass in young and middleaged essential hypertensives[J]. J Hum Hypertens,2003,17:231-238.
15.	RIZZO V, DI MAIO F, PETRETTO F, et al. Ambulatory pulse pressure, left ventricular hypertrophy and function in arterial hypertension[J]. Echocardiography,2004,21:11-16.
16.	VERDECCHIA P, SCHILLACI G, BORGIONI C, et al. Adrerse prognostic significance of concentiric remodeling of the left ventricle in hypertensive patients with normal left ventricular mass[J]. J Am Coll Cardiol, 1995, 25: 871-878.
17.	丁国峰, 孙运爱, 武金莲, 等. 氨氯地平治疗高血压及逆转左室肥厚作用的临床研究[J]. 心血管康复医学杂志, 2004, 13(2): 163-165.
18.	BRAZ NOGUEIRA J. Regression of left ventricular hypertrophy in hypertensiondoes it reduce cardiovascular risk[J]? Rev Port Cardiol, 2005, 24 (728): 1007-1013.
19.	STANTON AV. Prediction of cardiovascular damage in hypertensive patients clinic or ambulatory blood pressure[J]?J Hum Hypertens, 1999, 13(9): 81.

1. ASMAR R. Pulse pressure and aortic pulse wave are markers of cardiovascular risk in hypertensive populations[J]. Am J Hypertens,2001,14 (2):91-97.
2. KHATTAR. Value of ambulatory imtra arterial blood pressure monitoring in the long term prediction of left ventricular hypertophy and carotid atherosclerosis in essential hypertension[J]. J Hum Hypertens,1999,13 (2):111 – 116.
3. VERDECCHIA P,SCHILLACI G,BORGIONI C,et al. Ambulartory pulse pressure: a potent predicition of total cardio vascular risk in hypertension[J]. Hypertension,1998,32 (6):983- 988.
4. 刘力生.中国高血压防治指南[M]. 北京:人民卫生出版社,2005: 14.
5. OTELIO SR, NICO W, GERARD CB, et al. Reliability of stroke volume to pulse pressure ratio for estimating and detecting changes in arterial compliance[J].J Hypertens,1986,4(Suppl 5):S293-S296.
6. ALDERMAN MH. A new medel of risk:implication of increasing pulse pressure and systolic blood pressure on cardiovascular disease[J]. J Hypertension,1999,17 (Suppl5):25-28.
7. BOUTOUYRIE P,BUSSY C,LACOLLY P,et al.Association between local pulse pressure,mean blood pressure and large artiry remodeling[J]. Circulation,1999,100 (13):1387.
8. KHATTAR RS,ACHARYA DU,KINSEY C,et al. Congitudinal association of ambulatory pluse pressure with left ventricular mass and vascular hypertrouy in essential hypertension[J]. J Hypertens,1997,15 (7):707-743.
9. FRANKLIN SS, GUSTIN W4T H, WONG ND, et al. Hemodynamic patterns of agerelated changes in blood pressure. The Framingham study[J]. Circulation,1997,96:308-315.
10. KHATTAR. Value of ambulatory imtra arterial blood pressure monitoring in the long term prediction of left ventricular hypertophy and carotid atherosclerosis in essential hypertension[J]. J Hum Hypertens,1999,13 (2):111-116.
11. O’ROURKE MF, HAYWARD CS, LEHMAN ED, et al. Arterial stiffness. In:Oparil S,Weber MA, eds, Hypertension:a companion to Brenner & Rector’s Kidney[J]. Sauders,2000:134-151.
12. GELENTANO A, PALMIERI V, PALMA EN, et al.. Relations of pulse pressure and other components of blood pressure to preclinical echocardiographic abnormalities[J].J Hypertens,2002,20: 531-537.
13. JOKINIITTY JM, TUOMISTO MT, MAJAHALME SK, et al.. Pulse pressure responses to psychological tasks improve the prediction of left ventricular mass: 10 years of followup[J].J Hypertens,2003,21:789-795.
14. MULE G, NARDI E, ANDRONICO G, et al. Pul satile and steady 24 h blood pressure components as determinants of left ventricular mass in young and middleaged essential hypertensives[J]. J Hum Hypertens,2003,17:231-238.
15. RIZZO V, DI MAIO F, PETRETTO F, et al. Ambulatory pulse pressure, left ventricular hypertrophy and function in arterial hypertension[J]. Echocardiography,2004,21:11-16.
16. VERDECCHIA P, SCHILLACI G, BORGIONI C, et al. Adrerse prognostic significance of concentiric remodeling of the left ventricle in hypertensive patients with normal left ventricular mass[J]. J Am Coll Cardiol, 1995, 25: 871-878.
17. 丁国峰, 孙运爱, 武金莲, 等. 氨氯地平治疗高血压及逆转左室肥厚作用的临床研究[J]. 心血管康复医学杂志, 2004, 13(2): 163-165.
18. BRAZ NOGUEIRA J. Regression of left ventricular hypertrophy in hypertensiondoes it reduce cardiovascular risk[J]? Rev Port Cardiol, 2005, 24 (728): 1007-1013.
19. STANTON AV. Prediction of cardiovascular damage in hypertensive patients clinic or ambulatory blood pressure[J]?J Hum Hypertens, 1999, 13(9): 81.

West China Medical Journal

Impact of Pulse Pressure on Left Ventricular Hypertrophy in Senile Patients with Essential Hypertension

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