目的:研究替米沙坦对合并高血压的阵发性房颤患者转复为窦性心律后复发的影响。方法: 选择84例合并高血压的阵发性房颤患者,随机分成观察组及对照组,观察组降压药使用替米沙坦,对照组使用氨氯地平,两组均使用胺碘酮复律,随访2年,观察两组患者的疗效及超声心动图(左房内径)变化。结果:观察组治疗合并高血压的阵发性房颤复发率显著低于对照组。结论:替米沙坦联合抗心律失常药物,能有效防止房颤复发,维持窦性心律。
Citation:
XU Li,BAI Ping.. Clinical Study on Telmisartan for the Treatment of Paroxysmal Atrial Fibrillation with Hypertension. West China Medical Journal, 2009, 24(8): 2130-2131. doi:
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- 1. 杜昕,马长生.心房颤动的再认识(一)[J].中国心血管病研究杂志,2005, 3(10): 725-727.
- 2. AUSMA J,DISPERSYN G,HANSD,et al. Changes in ultrastructural calcium distribution in goat atrial during atrial fibrillation[J].Mol Cell Cardiol,2000,32: 355-359.
- 3. 戚文航. 血管紧张素受体拮抗剂与心房颤动[J].中华心血管病杂志, 2004,32 (11): 1042-1043.
- 4. HIDEKO N, KOICKIRO K,HIDENORI U, et al. Angiotensin II antagonist prevents electrical remodeling in atrial fibrillation[J]. Circulation,2000,101: 2612-2617.