Citation: 许峰,周继陶. Current Status of Treatment and Progress of Radiotherapy for Local Recurrence of Rectal Cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2013, 20(11): 1217-1221. doi: Copy
1. | Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012[J]. CA Cancer J Clin, 2012, 62(1):10-29. doi:10. 3322/caac. 20138. |
2. | 陈万青, 郑荣寿, 张思维, 等. 2003~2007年中国癌症发病分析[J]. 中国肿瘤, 2012, 21(3):161-170. |
3. | 吴菲, 林国桢, 张晋昕. 我国恶性肿瘤发病现状及趋势[J]. 中国肿瘤, 2012, 21(2):81-85. |
4. | 赖少清, 鞠凤环, 王贵齐, 等. 2004-2008年大肠癌临床流行特征[J]. 中国肿瘤, 2010, 19(2):111-113. |
5. | 姜世雄, 王锡山, 耿长辉, 等. 3 607例结直肠癌病例的临床特征变化分析[J]. 癌症, 2009, 28(1):69-72. |
6. | Douglass HO Jr, Moertel CG, Mayer RJ, et al. Survival after postoperative combination treatment of rectal cancer[J]. N Engl J Med, 1986, 315(20):1294-1295. |
7. | Palmer G, Martling A, Cedermark B, et al. A population-based study on the management and outcome in patients with locally recurrent rectal cancer[J]. Ann Surg Oncol, 2007, 14(2):447-454. |
8. | Kapiteijn E, Marijnen CA, Nagtegaal ID, et al. Preoperative radiotherapy combined with total mesorectal excision for resectablerectal cancer[J]. N Engl J Med, 2001, 345(9):638-646. |
9. | Sauer R, Becker H, Hohenberger W, et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer[J]. N Engl J Med, 2004, 351(17):1731-1740. |
10. | van den Brink M, Stiggelbout AM, van den Hout WB, et al. Clinical nature and prognosis of locally recurrent rectal cancer after total mesorectal excision with or without preoperative radiotherapy[J]. J Clin Oncol, 2004, 22(19):3958-3964. |
11. | Boyle KM, Sagar PM, Chalmers AG, et al. Surgery for locally recurrent rectal cancer[J]. Dis Colon Reetum, 2005, 48(5):929-937. |
12. | Huguier M, Houry S, Barrier A. Local recurrence of cancer of the rectum[J]. Am Surg, 2001, 182(5):437-439. |
13. | Bentzen SM, Balslev I, Pedersen M, et al. Time to loco-regional recurrence after resection of Dukes’ B and C colorectal cancerwith or without adjuvant postoperative radiotherapy. A multivar-iate regression analysis[J]. Br J Cancer, 1992, 65(1):102-107. |
14. | McCall JL, Cox MR, Wattchow DA. Analysis of local recurrencerates after surgery alone for rectal cancer[J]. Int J Colorectal Dis, 1995, 10(3):126-132. |
15. | den Dulk M, Marijnen CA, Putter H, et al. Risk factors for adverseoutcome in patients with rectal cancer treated with an abdominoperineal resection in the total mesorectal excision trial[J]. Ann Surg, 2007, 246(1):83-90. |
16. | Hahnloser D, Nelson H, Gunderson LL, et al. Curative potential of multimodality therapy for locally recurrent rectal cancer[J]. Ann Surg, 2003, 237(4):502-508. |
17. | Mohiuddin M, Marks G, Marks J. Long-term results of reirradiation for patients with recurrent rectal carcinoma[J]. Cancer, 2002, 95(5):1144-1150. |
18. | Kim YW, Kim NK, Min BS, et al. Factors associated with anastomotic recurrence after total mesorectal excision in rectal cancer patients[J]. J Surg Oncol, 2009, 99(1):58-64. |
19. | Hashiguchi Y, Sekine T, Sakamoto H, et al. Intraoperative irra-diation after surgery for locally recurrent rectal cancer[J]. Dis Colon Rectum, 1999, 42(7):886-893. |
20. | Markus J, Morrissey B, deGara C, et al. MRI of recurrent recto-sigmoid carcinoma[J]. Abdom Imaging, 1997, 22(3):338-342. |
21. | Giovannini M, Bernardini D, Seitz JF, et al. Value of endoscopicultrasonography for assessment of patients presenting elevatedtumor marker levels after surgery for colorectal cancers[J]. Endo-scopy, 1998, 30(5):469-476. |
22. | Nielsen MB, Laurberg S, Holm T. Current management of locallyrecurrent rectal cancer[J]. Colorectal Dis, 2011, 13(7):732-742. |
23. | Asoglu O, Karanlik H, Muslumanoglu M, et al. Prognostic and predictive factors after surgical treatment for locally recurrent rectalcancer:a single institute experience[J]. Eur J Surg Oncol, 2007,. |
24. | Zhao J, Du CZ, Sun YS, et al. Patterns and prognosis of locally recurrent rectal cancer following multidisciplinary treatment[J]. World J Gastroenterol, 2012, 18(47):7015-7020. doi:10.3748/wjg. v18. i47. 7015. |
25. | Dresen RC, Gosens MJ, Martijn H, et al. Radical resection after IORT-containing multimodality treatment is the most important determinant for outcome in patients treated for locally recurrent rectal cancer[J]. Ann Surg Oncol, 2008, 15(7):1937-1947. |
26. | Vermaas M, Ferenschild FT, Nuyttens JJ, et al. Preoperative radiotherapy improves outcome in recurrent rectal cancer[J]. DisColon Rectum, 2005, 48(5):918-928. |
27. | Hansen MH, Balteskard L, Dørum LM, et al. Locally recurrent rectal cancer in Norway[J]. Br J Surg, 2009, 96(10):1176-1182. |
28. | Kusters M, Dresen RC, Martijn H, et al. Radicality of resection and survival after multimodality treatment is influenced by subsite of locally recurrent rectal cancer[J]. Int J Radiat Oncol Biol Phys, 2009, 75(5):1444-1449. |
29. | Bosset JF, Calais G, Mineur L, et al. Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer:preliminary results-EORTC 22921[J]. J Clin Oncol, 2005, 23(24):5620-5627. |
30. | Tulchinsky H, Shmueli E, Figer A, et al. An interval >7 weeks between neoadjuvant therapy and surgery improves pathologic complete response and disease-free survival in patients with locallyadvanced rectal cancer[J]. Ann Surg Oncol, 2008, 15(10):2661-2667. |
31. | Valentini V, Morganti AG, Gambacorta MA, et al. Preoperative hyperfractionated chemoradiation for locally recurrent rectal cancerin patients previously irradiated to the pelvis:A multicentric phaseⅡstudy[J]. Int J Radiat Oncol Biol Phys, 2006, 64(4):1129-1139. |
32. | Moriya Y. Treatment strategy for locally recurrent rectal cancer[J]. Jpn J Clin Oncol, 2006, 36(3):127-131. |
33. | (10):1199-1206. |
34. | Folkesson J, Birgisson H, Pahlman L, et al. Swedish rectal cancertrial:long lasting benefits from radiotherapy on survival and local recurrence rate[J]. J Clin Oncol, 2005, 23(24):5644-5650. |
35. | Mohiuddin M, Marks GM, Lingareddy V, et al. Curative surgicalresection following reirradiation for recurrent rectal cancer[J]. Int J Radiat Oncol Biol Phys, 1997, 39(3):643-649. |
36. | Haddock MG, Gunderson LL, Nelson H, et al. Intraoperative irradiation for locally recurrent colorectal cancer in previouslyirradiated patients[J]. Int J Radiat Oncol Biol Phys, 2001, 49(5):. |
37. | Glimelius B. Recurrent rectal cancer. The pre-irradiated primary tumour:can more radiotherapy be given?[J]. Colorectal Dis, 2003, 5(5):501-503. |
38. | Gunderson LL, Nelson H, Martenson JA, et al. Intraoperative electron and external beam irradiation with or without 5-fluorouraciland maximum surgical resection for previously unirradiated,locally recurrent colorectal cancer[J]. Dis Colon Rectum, 1996,. |
39. | Alektiar KM, Zelefsky MJ, Paty PB, et al. High-dose-rate intraoperative brachytherapy for recurrent colorectal cancer[J]. Int J Radiat Oncol Biol Phys, 2000, 48(1):219-226. |
40. | (12):1379-1395. |
41. | Nuyttens JJ, Kolkman-Deurloo IK, Vermaas M, et al. High-dose-rate intraoperative radiotherapy for close or positive margins in patients with locally advanced or recurrent rectal cancer[J]. Int J Radiat Oncol Biol Phys, 2004, 58(1):106-112. |
42. | Mannaerts GH, Rutten HJ, Martijn H, et al. Comparison of intra-operative radiation therapy-containing multimodality treatment with historical treatment modalities for locally recurrent rectal cancer[J]. Dis Colon Rectum, 2001, 44(12):1749-1758. |
43. | Shoup M, Guillem JG, Alektiar KM, et al. Predictors of survivalin recurrent rectal cancer after resection and intraoperative radiotherapy[J]. Dis Colon Rectum, 2002, 45(5):585-592. |
44. | Treiber M, Lehnert T, Oertel S, et al. Intraoperative radiotherapy-special focus:recurrent rectal carcinoma[J]. Front Radiat Ther Oncol, 2004, 38:52-56. |
45. | Wiig JN, Tveit KM, Poulsen JP, et al. Preoperative irradiation and surgery for recurrent rectal cancer. Will intraoperative radiotherapy (IORT) be of additional benefit? A prospective study[J]. Radiother Oncol, 2002, 62(2):207-213. |
46. | Mannaerts GH, Martijn H, Crommelin MA, et al. Intraoperativeelectron beam radiation therapy for locally recurrent rectal carcinoma[J]. Int J Radiat Oncol Biol Phys, 1999, 45(2):297-308. |
47. | Lindel K, Willett CG, Shellito PC, et al. Intraoperative radiationtherapy for locally advanced recurrent rectal or rectosigmoid cancer[J]. Radiother Oncol, 2001, 58(1):83-87.. |
48. | Ellis RJ, Nag S, Kinsella TJ. Alternative techniques of intraoperative radiotherapy[J]. Eur J Surg Oncol, 2000, 26 Suppl A:S25-S27. |
49. | Harrison LB, Enker WE, Anderson LL. High-dose-rate intraoperative radiation therapy for colorectal cancer[J]. Oncology (Williston Park), 1995, 9(8):737-741. |
50. | 汪丽燕, 李滨, 庄丽维, 等. 三维适形放疗联合化疗治疗术后复发性直肠癌的临床观察[J]. 中华肿瘤防治杂志, 2010, 17(18):1473-1475. |
51. | 杨燕光, 蔡晶, 何晓军, 等. 三维适形放疗联合同步化疗治疗直肠癌术后复发[J]. 肿瘤学杂志, 2012, 18(5):349-352. |
52. | 张培良, 张佃富. 简化调强放疗同步卡培他滨治疗直肠癌术后复发临床观察[J]. 中华肿瘤防治杂志, 2012, 19(14):1103-1105. |
53. | Kim MS, Choi C, Yoo S, et al. Stereotactic body radiation therapy in patients with pelvic recurrence from rectal carcinoma[J]. Jpn J Clin Oncol, 2008, 38(10):695-700. |
54. | Jingu K, Ariga H, Kaneta T, et al. Focal dose escalation using FDG-PET-guided intensity-modulated radiation therapy boost for postoperative local recurrent rectal cancer:a planning study with comparison of DVH and NTCP[J]. BMC Cancer, 2010, 10:127. doi:10.1186/1471-2407-10-127. |
55. | -1274. |
- 1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012[J]. CA Cancer J Clin, 2012, 62(1):10-29. doi:10. 3322/caac. 20138.
- 2. 陈万青, 郑荣寿, 张思维, 等. 2003~2007年中国癌症发病分析[J]. 中国肿瘤, 2012, 21(3):161-170.
- 3. 吴菲, 林国桢, 张晋昕. 我国恶性肿瘤发病现状及趋势[J]. 中国肿瘤, 2012, 21(2):81-85.
- 4. 赖少清, 鞠凤环, 王贵齐, 等. 2004-2008年大肠癌临床流行特征[J]. 中国肿瘤, 2010, 19(2):111-113.
- 5. 姜世雄, 王锡山, 耿长辉, 等. 3 607例结直肠癌病例的临床特征变化分析[J]. 癌症, 2009, 28(1):69-72.
- 6. Douglass HO Jr, Moertel CG, Mayer RJ, et al. Survival after postoperative combination treatment of rectal cancer[J]. N Engl J Med, 1986, 315(20):1294-1295.
- 7. Palmer G, Martling A, Cedermark B, et al. A population-based study on the management and outcome in patients with locally recurrent rectal cancer[J]. Ann Surg Oncol, 2007, 14(2):447-454.
- 8. Kapiteijn E, Marijnen CA, Nagtegaal ID, et al. Preoperative radiotherapy combined with total mesorectal excision for resectablerectal cancer[J]. N Engl J Med, 2001, 345(9):638-646.
- 9. Sauer R, Becker H, Hohenberger W, et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer[J]. N Engl J Med, 2004, 351(17):1731-1740.
- 10. van den Brink M, Stiggelbout AM, van den Hout WB, et al. Clinical nature and prognosis of locally recurrent rectal cancer after total mesorectal excision with or without preoperative radiotherapy[J]. J Clin Oncol, 2004, 22(19):3958-3964.
- 11. Boyle KM, Sagar PM, Chalmers AG, et al. Surgery for locally recurrent rectal cancer[J]. Dis Colon Reetum, 2005, 48(5):929-937.
- 12. Huguier M, Houry S, Barrier A. Local recurrence of cancer of the rectum[J]. Am Surg, 2001, 182(5):437-439.
- 13. Bentzen SM, Balslev I, Pedersen M, et al. Time to loco-regional recurrence after resection of Dukes’ B and C colorectal cancerwith or without adjuvant postoperative radiotherapy. A multivar-iate regression analysis[J]. Br J Cancer, 1992, 65(1):102-107.
- 14. McCall JL, Cox MR, Wattchow DA. Analysis of local recurrencerates after surgery alone for rectal cancer[J]. Int J Colorectal Dis, 1995, 10(3):126-132.
- 15. den Dulk M, Marijnen CA, Putter H, et al. Risk factors for adverseoutcome in patients with rectal cancer treated with an abdominoperineal resection in the total mesorectal excision trial[J]. Ann Surg, 2007, 246(1):83-90.
- 16. Hahnloser D, Nelson H, Gunderson LL, et al. Curative potential of multimodality therapy for locally recurrent rectal cancer[J]. Ann Surg, 2003, 237(4):502-508.
- 17. Mohiuddin M, Marks G, Marks J. Long-term results of reirradiation for patients with recurrent rectal carcinoma[J]. Cancer, 2002, 95(5):1144-1150.
- 18. Kim YW, Kim NK, Min BS, et al. Factors associated with anastomotic recurrence after total mesorectal excision in rectal cancer patients[J]. J Surg Oncol, 2009, 99(1):58-64.
- 19. Hashiguchi Y, Sekine T, Sakamoto H, et al. Intraoperative irra-diation after surgery for locally recurrent rectal cancer[J]. Dis Colon Rectum, 1999, 42(7):886-893.
- 20. Markus J, Morrissey B, deGara C, et al. MRI of recurrent recto-sigmoid carcinoma[J]. Abdom Imaging, 1997, 22(3):338-342.
- 21. Giovannini M, Bernardini D, Seitz JF, et al. Value of endoscopicultrasonography for assessment of patients presenting elevatedtumor marker levels after surgery for colorectal cancers[J]. Endo-scopy, 1998, 30(5):469-476.
- 22. Nielsen MB, Laurberg S, Holm T. Current management of locallyrecurrent rectal cancer[J]. Colorectal Dis, 2011, 13(7):732-742.
- 23. Asoglu O, Karanlik H, Muslumanoglu M, et al. Prognostic and predictive factors after surgical treatment for locally recurrent rectalcancer:a single institute experience[J]. Eur J Surg Oncol, 2007,.
- 24. Zhao J, Du CZ, Sun YS, et al. Patterns and prognosis of locally recurrent rectal cancer following multidisciplinary treatment[J]. World J Gastroenterol, 2012, 18(47):7015-7020. doi:10.3748/wjg. v18. i47. 7015.
- 25. Dresen RC, Gosens MJ, Martijn H, et al. Radical resection after IORT-containing multimodality treatment is the most important determinant for outcome in patients treated for locally recurrent rectal cancer[J]. Ann Surg Oncol, 2008, 15(7):1937-1947.
- 26. Vermaas M, Ferenschild FT, Nuyttens JJ, et al. Preoperative radiotherapy improves outcome in recurrent rectal cancer[J]. DisColon Rectum, 2005, 48(5):918-928.
- 27. Hansen MH, Balteskard L, Dørum LM, et al. Locally recurrent rectal cancer in Norway[J]. Br J Surg, 2009, 96(10):1176-1182.
- 28. Kusters M, Dresen RC, Martijn H, et al. Radicality of resection and survival after multimodality treatment is influenced by subsite of locally recurrent rectal cancer[J]. Int J Radiat Oncol Biol Phys, 2009, 75(5):1444-1449.
- 29. Bosset JF, Calais G, Mineur L, et al. Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer:preliminary results-EORTC 22921[J]. J Clin Oncol, 2005, 23(24):5620-5627.
- 30. Tulchinsky H, Shmueli E, Figer A, et al. An interval >7 weeks between neoadjuvant therapy and surgery improves pathologic complete response and disease-free survival in patients with locallyadvanced rectal cancer[J]. Ann Surg Oncol, 2008, 15(10):2661-2667.
- 31. Valentini V, Morganti AG, Gambacorta MA, et al. Preoperative hyperfractionated chemoradiation for locally recurrent rectal cancerin patients previously irradiated to the pelvis:A multicentric phaseⅡstudy[J]. Int J Radiat Oncol Biol Phys, 2006, 64(4):1129-1139.
- 32. Moriya Y. Treatment strategy for locally recurrent rectal cancer[J]. Jpn J Clin Oncol, 2006, 36(3):127-131.
- 33. (10):1199-1206.
- 34. Folkesson J, Birgisson H, Pahlman L, et al. Swedish rectal cancertrial:long lasting benefits from radiotherapy on survival and local recurrence rate[J]. J Clin Oncol, 2005, 23(24):5644-5650.
- 35. Mohiuddin M, Marks GM, Lingareddy V, et al. Curative surgicalresection following reirradiation for recurrent rectal cancer[J]. Int J Radiat Oncol Biol Phys, 1997, 39(3):643-649.
- 36. Haddock MG, Gunderson LL, Nelson H, et al. Intraoperative irradiation for locally recurrent colorectal cancer in previouslyirradiated patients[J]. Int J Radiat Oncol Biol Phys, 2001, 49(5):.
- 37. Glimelius B. Recurrent rectal cancer. The pre-irradiated primary tumour:can more radiotherapy be given?[J]. Colorectal Dis, 2003, 5(5):501-503.
- 38. Gunderson LL, Nelson H, Martenson JA, et al. Intraoperative electron and external beam irradiation with or without 5-fluorouraciland maximum surgical resection for previously unirradiated,locally recurrent colorectal cancer[J]. Dis Colon Rectum, 1996,.
- 39. Alektiar KM, Zelefsky MJ, Paty PB, et al. High-dose-rate intraoperative brachytherapy for recurrent colorectal cancer[J]. Int J Radiat Oncol Biol Phys, 2000, 48(1):219-226.
- 40. (12):1379-1395.
- 41. Nuyttens JJ, Kolkman-Deurloo IK, Vermaas M, et al. High-dose-rate intraoperative radiotherapy for close or positive margins in patients with locally advanced or recurrent rectal cancer[J]. Int J Radiat Oncol Biol Phys, 2004, 58(1):106-112.
- 42. Mannaerts GH, Rutten HJ, Martijn H, et al. Comparison of intra-operative radiation therapy-containing multimodality treatment with historical treatment modalities for locally recurrent rectal cancer[J]. Dis Colon Rectum, 2001, 44(12):1749-1758.
- 43. Shoup M, Guillem JG, Alektiar KM, et al. Predictors of survivalin recurrent rectal cancer after resection and intraoperative radiotherapy[J]. Dis Colon Rectum, 2002, 45(5):585-592.
- 44. Treiber M, Lehnert T, Oertel S, et al. Intraoperative radiotherapy-special focus:recurrent rectal carcinoma[J]. Front Radiat Ther Oncol, 2004, 38:52-56.
- 45. Wiig JN, Tveit KM, Poulsen JP, et al. Preoperative irradiation and surgery for recurrent rectal cancer. Will intraoperative radiotherapy (IORT) be of additional benefit? A prospective study[J]. Radiother Oncol, 2002, 62(2):207-213.
- 46. Mannaerts GH, Martijn H, Crommelin MA, et al. Intraoperativeelectron beam radiation therapy for locally recurrent rectal carcinoma[J]. Int J Radiat Oncol Biol Phys, 1999, 45(2):297-308.
- 47. Lindel K, Willett CG, Shellito PC, et al. Intraoperative radiationtherapy for locally advanced recurrent rectal or rectosigmoid cancer[J]. Radiother Oncol, 2001, 58(1):83-87..
- 48. Ellis RJ, Nag S, Kinsella TJ. Alternative techniques of intraoperative radiotherapy[J]. Eur J Surg Oncol, 2000, 26 Suppl A:S25-S27.
- 49. Harrison LB, Enker WE, Anderson LL. High-dose-rate intraoperative radiation therapy for colorectal cancer[J]. Oncology (Williston Park), 1995, 9(8):737-741.
- 50. 汪丽燕, 李滨, 庄丽维, 等. 三维适形放疗联合化疗治疗术后复发性直肠癌的临床观察[J]. 中华肿瘤防治杂志, 2010, 17(18):1473-1475.
- 51. 杨燕光, 蔡晶, 何晓军, 等. 三维适形放疗联合同步化疗治疗直肠癌术后复发[J]. 肿瘤学杂志, 2012, 18(5):349-352.
- 52. 张培良, 张佃富. 简化调强放疗同步卡培他滨治疗直肠癌术后复发临床观察[J]. 中华肿瘤防治杂志, 2012, 19(14):1103-1105.
- 53. Kim MS, Choi C, Yoo S, et al. Stereotactic body radiation therapy in patients with pelvic recurrence from rectal carcinoma[J]. Jpn J Clin Oncol, 2008, 38(10):695-700.
- 54. Jingu K, Ariga H, Kaneta T, et al. Focal dose escalation using FDG-PET-guided intensity-modulated radiation therapy boost for postoperative local recurrent rectal cancer:a planning study with comparison of DVH and NTCP[J]. BMC Cancer, 2010, 10:127. doi:10.1186/1471-2407-10-127.
- 55. -1274.