1. |
Ferlay J, Autier P, Boniol M, et al. Estimates of the cancer inci-dence and mortality in Europe in 2006[J]. Ann Oncol, 2007, 18(3):581-592.
|
2. |
Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2009[J]. CA Cancer J Clin, 2009, 59(4):225-249.
|
3. |
吴菲, 林国桢, 张晋昕. 我国恶性肿瘤发病现状及趋势[J]. 中国肿瘤, 2012, 21(2):81-85.
|
4. |
Schepeler T, Reinert JT, Ostenfeld MS, et al. Diagnostic and prognostic microRNAs in stageⅡcolon cancer[J]. Cancer Res, 2008, 68(15):6416-6424.
|
5. |
Slaby O, Svoboda M, Fabian P, et al. Altered expression of miR-21,miR-31, miR-143 and miR-145 is related to clinicopathologicfeatures of colorectal cancer[J]. Oncology, 2007, 72(5-6):397-402.
|
6. |
Esquela-Kerscher A, Slack FJ. Oncomirs-microRNAs with a role in cancer[J]. Nat Rev Cancer, 2006, 6(4):259-269.
|
7. |
Lund E, Güttinger S, Calado A, et al. Nuclear export of microRNA precursors[J]. Science, 2004, 303(5654):95-98.
|
8. |
(8):e43452.
|
9. |
He L, Hannon GJ. MicroRNAs:small RNAs with a big role in gene regulation[J]. Nat Rev Genet, 2004, 5(7):522-531.
|
10. |
Lai EC. MicroRNAs are complementary to 3′ UTR sequencemotifs that mediate negative post-transcriptional regulation[J]. NatGenet, 2002, 30(4):363-364.
|
11. |
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets[J]. Cell, 2005, 120(1):15-20.
|
12. |
Lim LP, Lau NC, Garrett-Engele P, et al. Microarray analysis shows that some microRNAs downregulate large numbers of targetmRNAs[J]. Nature, 2005, 433(7027):769-773.
|
13. |
Huang Q, Gumireddy K, Schrier M, et al. The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis[J]. Nat Cell Biol, 2008, 10(2):202-210.
|
14. |
Hashimoto Y, Akiyama Y, Yuasa Y. Multiple-to-multiple relati-onships between microRNAs and target genes in gastric cancer[J]. PLoS One, 2013, 8(5):e62589.
|
15. |
Iwaya T, Yokobori T, Nishida N, et al. Downregulation of miR-144 is associated with colorectal cancer progression via activation of mTOR signaling pathway[J]. Carcinogenesis, 2012, 33(12):2391-2397.
|
16. |
Zhang GJ, Xiao HX, Tian HP, et al. Upregulation of microRNA-.
|
17. |
Chiang Y, Song Y, Wang Z, et al. microRNA-192, -194 and -215are frequently downregulated in colorectal cancer[J]. Exp Ther Med, 2012, 3(3):560-566.
|
18. |
Nakajima G, Hayashi K, Xi Y, et al. Non-coding microRNAs hsa-let-7g and hsa-miR-181b are associated with chemoresponse to S-1 in colon cancer[J]. Cancer Genomics Proteomics, 2006, 3(5):317-324.
|
19. |
Díaz R, Silva J, García JM, et al. Deregulated expression of miR-106a predicts survival in human colon cancer patients[J]. Genes Chromosomes Cancer, 2008, 47(9):794-802.
|
20. |
Shibuya H, Iinuma H, Shimada R, et al. Clinicopathological and prognostic value of microRNA-21 and microRNA-155 in colorectalcancer[J]. Oncology, 2010, 79(3-4):313-320.
|
21. |
Schetter AJ, Leung SY, Sohn JJ, et al. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colonadenocarcinoma[J]. JAMA, 2008, 299(4):425-436.
|
22. |
Huang Z, Huang D, Ni S, et al. Plasma microRNAs are promisingnovel biomarkers for early detection of colorectal cancer[J]. Int J Cancer, 2010, 127(1):118-126.
|
23. |
Wang CJ, Zhou ZG, Wang L, et al. Clinicopathological significance of microRNA-31, -143 and -145 expression in colorectal cancer[J]. Dis Markers, 2009, 26(1):27-34.
|
24. |
Pichler M, Winter E, Stotz M, et al. Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer[J]. Br J Cancer, 2012, 106(11):1826-1832.
|
25. |
Xi Y, Formentini A, Chien M, et al. Prognostic values of microRNAs in colorectal cancer[J]. Biomark Insights, 2006, 2:113-121.
|
26. |
Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008:GLOBOCAN 2008[J]. Int J Cancer, 2010, 127(12):2893-2917.
|
27. |
Lieberman DA. Clinical practice. Screening for colorectal cancer[J]. N Engl J Med, 2009, 361(12):1179-1187.
|
28. |
Nishiumi S, Kobayashi T, Ikeda A, et al. A novel serum metabo-lomics-based diagnostic approach for colorectal cancer[J]. PLoSOne, 2012, 7(7):e40459.
|
29. |
Chen C, Ridzon DA, Broomer AJ, et al. Real-time quantificationof microRNAs by stem-loop RT-PCR[J]. Nucleic Acids Res, 2005, 33(20):e179.
|
30. |
Link A, Balaguer F, Shen Y, et al. Fecal microRNAs as novel biomarkers for colon cancer screening[J]. Cancer Epidemiol Biomarkers Prev, 2010, 19(7):1766-1774.
|
31. |
Kanaan Z, Rai SN, Eichenberger MR, et al. Plasma miR-21:a potential diagnostic marker of colorectal cancer[J]. Ann Surg, 2012, 256(3):544-551.
|
32. |
Cheng H, Zhang L, Cogdell DE, et al. Circulating plasma miR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis[J]. PLoS One, 2011, 6(3):e17745.
|
33. |
increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells[J]. BMC Cancer, 2010, 10:616.
|
34. |
Pu XX, Huang GL, Guo HQ, et al. Circulating miR-221 directly amplified from plasma is a potential diagnostic and prognostic marker of colorectal cancer and is correlated with p53 expression[J]. Gastroenterol Hepatol, 2010, 25(10):1674-1680.
|
35. |
Wang LG, Gu J. Serum microRNA-29a is a promising novel marker for early detection of colorectal liver metastasis[J]. CancerEpidemiol, 2012, 36(1):e61-e67.
|
36. |
Koga Y, Yasunaga M, Takahashi A, et al. MicroRNA expression profiling of exfoliated colonocytes isolated from feces for colorectal cancer screening[J]. Cancer Prev Res (Phila), 2010, 3(11):1435-1442.
|
37. |
Wu CW, Ng SS, Dong YJ, et al. Detection of miR-92a and miR-21 in stool samples as potential screening biomarkers for colorectal cancer and polyps[J]. Gut, 2012, 61(5):739-745.
|
38. |
Li JM, Zhao RH, Li ST, et al. Down-regulation of fecal miR-143and miR-145 as potential markers for colorectal cancer[J]. SaudiMed J, 2012, 33(1):24-29.
|
39. |
Ng EK, Chong WW, Jin H, et al. Differential expression of micro-RNAs in plasma of patients with colorectal cancer:a potential marker for colorectal cancer screening[J]. Gut, 2009, 58(10):1375-1381.
|
40. |
汪晓东, 曹霖, 曾天芳, 等. 多学科协作诊治模式下新辅助/辅助化疗联合结直肠癌手术的临床效果[J]. 中国普外基础与临床杂志, 2008, 15(8):615-619.
|
41. |
Aslam MI, Patel M, Singh B, et al. MicroRNA manipulation in colorectal cancer cells:from laboratory to clinical application[J]. J Transl Med, 2012, 10(1):128.
|
42. |
Weiler J, Hunziker J, Hall J. Anti-miRNA oligonucleotides (AMOs):ammunition to target miRNAs implicated in human disease?[J]. Gene Ther, 2006, 13(6):496-502.
|
43. |
Kauppinen S, Vester B, Wengel J. Locked nucleic acid:high-affinity targeting of complementary RNA for RNomics[J]. Handb Exp Pharmacol, 2006, (173):405-422.
|
44. |
Asangani IA, Rasheed SA, Nikolova DA, et al. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer[J]. Oncogene, 2008, 27(15):2128-2136.
|
45. |
Valeri N, Gasparini P, Braconi C, et al. MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2)[J]. Proc Natl Acad Sci U S A, 2010, 107(49):21098-21103.
|
46. |
Wang CJ, Stratmann J, Zhou ZG, et al. Suppression of microRNA-.
|
47. |
Ng EK, Tsang WP, Ng SS, et al. MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer[J]. Br J Cancer, 2009, 101(4):699-706.
|
48. |
Zhang J, Guo H, Zhang H, et al. Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene Friend leukemia virus integration 1 gene[J]. Cancer, 2011, 117(1):86-95.
|
49. |
Rossi L, Bonmassar E, Faraoni I. Modification of miR gene expr-ession pattern in human colon cancer cells following exposure to 5-fluorouracil in vitro[J]. Pharmacol Res, 2007, 56(3):248-253.
|
50. |
Liu K, Li G, Fan C, et al. Increased expression of microRNA-21and its association with chemotherapeutic response in human colo-rectal cancer[J]. J Int Med Res, 2011, 39(6):2288-2295.
|
51. |
Borralho PM, Kren BT, Castro RE, et al. MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells[J]. FEBS J, 2009, 276(22):6689-6700.
|
52. |
Feng B, Dong TT, Wang LL, et al. Colorectal cancer migrationand invasion initiated by microRNA-106a[J]. PLoS One, 2012,.
|
53. |
promotes the migration and invasion of colorectal cancer cells through the regulation of claudin-1 expression[J]. Int J Mol Med,.
|
54. |
, 31(6):1375-1380.
|