Objective To compare the mean operative time and complications between the LigaSure device and Harmonic Scalpel during video-assisted endoscopic approaches thyroidectomy.
Methods The clinical data of 684 cases performed Miccoli thyroidectomy by the same operation team from January 2007 to December 2011 in the department of general surgery，Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University were analyzed. Three hundred and forty-nine patients were used Harmonic Scalpel，335 patients were used LigaSure device. The mean operative time and complications （such as hematoma，transient hoarseness，permanent recurrent laryngeal nerve injury，and hypocalcemia） were compared between two groups.
Results A total of 684 patients were included in the study，of whom 263 underwent total thyroidectomy and 421 underwent lobectomy. There were not significant differences of the operative time and the complications in both thyroidectomy and lobectomy between the LigaSure device and Harmonic Scalpel
（P＞0.05）.
Conclusions The uses of the LigaSure device and Harmonic Scalpel in thyroid surgery are safe and reliable，surgeons may choose surgical instruments by habits and medical equipments.
Citation：
ZHOU Yulong,HAN Xiaodong,DI Jianzhong,ZHANG Hongwei,DU Yibao,ZHANG Pin.. Application of LigaSure Versus Harmonic Scalpel in Miccoli Thyroidectomy. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(8): 860-863. doi:
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Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
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Ferri E， Armato E， Spinato G， et al. Focus harmonic scalpel compared to conventional haemostasis in open total thyroidectomy：A prospective randomized trial[J]. Int J Otolaryngol， 2011， 2011：1-7.
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Miccoli P， Pinchera A， Cecchini G， et al. Minimally invasive， video-assisted parathyroid surgery for primary hyperparathyroidism[J]. J Endocrinol Invest， 1997， 20(7)：429-430.
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Chang LY， O’Neill C， Suliburk J， et al. Sutureless total thyroidectomy：a safe and cost-effective alternative[J]. ANZ J Surg， 2011， 81(7-8)：510-514.
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Youssef T， Mahdy T， Farid M， et al. Thyroid surgery：use of the LigaSure Vessel Sealing System versus conventional knot tying[J]. Int J Surg， 2008， 6(4)：323-327.
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Ignjatović M， Kostić Z. Thyroidectomy with LigaSure[J]. Surg Today， 2011， 41(6)：767-773.
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Dilek ON， Yilmaz S， Degirmenci B， et al. The use of a vessel sealing system in thyroid surgery[J]. Acta Chir Belg， 2005， 105(4)：369-372.
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Smith CT， Zarebczan B， Alhefdhi A， et al. Infrared thermographic profiles of vessel sealing devices on thyroid parenchyma[J]. J Surg Res， 2011， 170(1)：64-68.
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Courtney KP， Gregory WH， Evren D， et al. Tissue response to surgical energy devices[J]. Urology， 2008， 71(4)：744-748.
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Pardal-Refoyo JL. Hemostatic systems in thyroid surgery and complications[J]. Acta Otorrinolaringol Esp， 2011， 62(5)：339-346.
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Maeda S， Shimizu K， Minami S， et al. Video-assisted neck surgery for thyroid and parathyroid diseases[J]. Biomed Pharmacother， 2002， 56 Suppl 1(Suppl 1)：92s-95s.
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魏涛， 朱精强. 甲状腺手术理念进展与新型手术器械在甲状腺外科中的应用[J]. 中国普外基础与临床杂志， 2011， 18(2)：220-224.
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Musunuru S， Schaefer S， Chen H. The use of the LigaSure for hemostasis during thyroid lobectomy[J]. Am J Surg， 2008， 195(3)：382-384.
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Miccoli P， Materazzi G， Miccoli M， et al. Evaluation of a new ultrasonic device in thyroid surgery：comparative randomized study[J]. Am J Surg， 2010， 199(6)：736-740.
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| 14. |
魏涛， 李志辉， 朱精强. 超声刀与传统方法在开放甲状腺手术的临床对比研究[J]. 中国普外基础与临床杂志， 2008， 15(5)：323-326.
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| 15. |
Mourad M， Rulli F， Robert A， et al. Randomized clinical trial on Harmonic Focus shears versus clamp-and-tie technique for total thyroidectomy[J]. Am J Surg， 2011， 202(2)：168-174.
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| 16. |
Zarebczan B， Mohanty D， Chen H. A comparison of the Liga Sure and harmonic scalpel in thyroid surgery：a single institution review[J]. Ann Surg Oncol， 2011， 18(1)：214-218.
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| 17. |
Manouras A， Markogiannakis H， Koutras AS， et al. Thyroid surgery：comparison between the electrothermal bipolar vessel sealing system， harmonic scalpel， and classic suture ligation[J]. Am J Surg， 2008， 195(1)：48-52.
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Shen WT， Baumbusch MA， Kebebew E， et al. Use of the electrothermal vessel sealing system versus standard vessel ligation in thyroidectomy[J]. Asian J Surg， 2005， 28(2)：86-89.
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O’Neill CJ， Chang LY， Suliburk JW， et al. Sutureless thyroidectomy：surgical technique[J]. ANZ J Surg， 2011， 81(7-8)：515-518.
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Lang HH， Yih CL， Hung KY. Does using an energized device in open thyroidectomy reduce complications?[J]. J Surg Res， 2012：e1-e7.
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Dionigi G， Rovera F， Carrafiello G， et al. New technologies in ambulatory thyroid surgery[J]. Int J Surg， 2008， 6 Suppl 1：S22-S25.
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| 22. |
Markogiannakis H， Kekis PB， Memos N， et al. Thyroid surgery with the new harmonic scalpel：a prospective randomized study[J]. Surgery， 2011， 149(3)：411-415.
|
| 23. |
Hartl DM. The place of new haemostatic techniques in thyroid surgery[J]. Eur Ann Otorhinolaryngol Head Neck Dis， 2011， 128(4)：200-202.
|
- 1. Ferri E， Armato E， Spinato G， et al. Focus harmonic scalpel compared to conventional haemostasis in open total thyroidectomy：A prospective randomized trial[J]. Int J Otolaryngol， 2011， 2011：1-7.
- 2. Miccoli P， Pinchera A， Cecchini G， et al. Minimally invasive， video-assisted parathyroid surgery for primary hyperparathyroidism[J]. J Endocrinol Invest， 1997， 20(7)：429-430.
- 3. Chang LY， O’Neill C， Suliburk J， et al. Sutureless total thyroidectomy：a safe and cost-effective alternative[J]. ANZ J Surg， 2011， 81(7-8)：510-514.
- 4. Youssef T， Mahdy T， Farid M， et al. Thyroid surgery：use of the LigaSure Vessel Sealing System versus conventional knot tying[J]. Int J Surg， 2008， 6(4)：323-327.
- 5. Ignjatović M， Kostić Z. Thyroidectomy with LigaSure[J]. Surg Today， 2011， 41(6)：767-773.
- 6. Dilek ON， Yilmaz S， Degirmenci B， et al. The use of a vessel sealing system in thyroid surgery[J]. Acta Chir Belg， 2005， 105(4)：369-372.
- 7. Smith CT， Zarebczan B， Alhefdhi A， et al. Infrared thermographic profiles of vessel sealing devices on thyroid parenchyma[J]. J Surg Res， 2011， 170(1)：64-68.
- 8. Courtney KP， Gregory WH， Evren D， et al. Tissue response to surgical energy devices[J]. Urology， 2008， 71(4)：744-748.
- 9. Pardal-Refoyo JL. Hemostatic systems in thyroid surgery and complications[J]. Acta Otorrinolaringol Esp， 2011， 62(5)：339-346.
- 10. Maeda S， Shimizu K， Minami S， et al. Video-assisted neck surgery for thyroid and parathyroid diseases[J]. Biomed Pharmacother， 2002， 56 Suppl 1(Suppl 1)：92s-95s.
- 11. 魏涛， 朱精强. 甲状腺手术理念进展与新型手术器械在甲状腺外科中的应用[J]. 中国普外基础与临床杂志， 2011， 18(2)：220-224.
- 12. Musunuru S， Schaefer S， Chen H. The use of the LigaSure for hemostasis during thyroid lobectomy[J]. Am J Surg， 2008， 195(3)：382-384.
- 13. Miccoli P， Materazzi G， Miccoli M， et al. Evaluation of a new ultrasonic device in thyroid surgery：comparative randomized study[J]. Am J Surg， 2010， 199(6)：736-740.
- 14. 魏涛， 李志辉， 朱精强. 超声刀与传统方法在开放甲状腺手术的临床对比研究[J]. 中国普外基础与临床杂志， 2008， 15(5)：323-326.
- 15. Mourad M， Rulli F， Robert A， et al. Randomized clinical trial on Harmonic Focus shears versus clamp-and-tie technique for total thyroidectomy[J]. Am J Surg， 2011， 202(2)：168-174.
- 16. Zarebczan B， Mohanty D， Chen H. A comparison of the Liga Sure and harmonic scalpel in thyroid surgery：a single institution review[J]. Ann Surg Oncol， 2011， 18(1)：214-218.
- 17. Manouras A， Markogiannakis H， Koutras AS， et al. Thyroid surgery：comparison between the electrothermal bipolar vessel sealing system， harmonic scalpel， and classic suture ligation[J]. Am J Surg， 2008， 195(1)：48-52.
- 18. Shen WT， Baumbusch MA， Kebebew E， et al. Use of the electrothermal vessel sealing system versus standard vessel ligation in thyroidectomy[J]. Asian J Surg， 2005， 28(2)：86-89.
- 19. O’Neill CJ， Chang LY， Suliburk JW， et al. Sutureless thyroidectomy：surgical technique[J]. ANZ J Surg， 2011， 81(7-8)：515-518.
- 20. Lang HH， Yih CL， Hung KY. Does using an energized device in open thyroidectomy reduce complications?[J]. J Surg Res， 2012：e1-e7.
- 21. Dionigi G， Rovera F， Carrafiello G， et al. New technologies in ambulatory thyroid surgery[J]. Int J Surg， 2008， 6 Suppl 1：S22-S25.
- 22. Markogiannakis H， Kekis PB， Memos N， et al. Thyroid surgery with the new harmonic scalpel：a prospective randomized study[J]. Surgery， 2011， 149(3)：411-415.
- 23. Hartl DM. The place of new haemostatic techniques in thyroid surgery[J]. Eur Ann Otorhinolaryngol Head Neck Dis， 2011， 128(4)：200-202.
