1. |
Harder J, Blum HE.. Cholangiocarcinoma [J]. Praxis (Bern 1994), 2002, 91(34): 13521356.
|
2. |
Maruyama R, Toyooka S, Toyooka KO, et al. Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features [J]. Clin Cancer Res, 2002, 8(2): 514519.
|
3. |
Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer [J]. Nat Rev Genet, 2002, 3(6): 415428.
|
4. |
Balmain A, Gray J, Ponder B. The genetics and genomics of cancer [J]. Nat Genet, 2003, 33 Suppl: 238244.
|
5. |
Singal R, Ginder GD. DNA methylation [J]. Blood, 1999, 93(12): 40594070.
|
6. |
Yang B, House MG, Guo M, et al. Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma [J]. Mod Pathol, 2005, 18(3): 412420.
|
7. |
Lee S, Kim WH, Jung HY, et al. Aberrant CpG island methylation of multiple genes in intrahepatic cholangiocarcinoma [J]. Am J Pathol, 2002, 161(3): 10151022.
|
8. |
Tozawa T, Tamura G, Honda T, et al. Promoter hypermethylation of DAPkinase is associated with poor survival in primary biliary tract carcinoma patients [J]. Cancer Sci, 2004, 95(9): 736740.
|
9. |
Isomoto H. Epigenetic alterations associated with cholangiocarcinoma (review) [J]. Oncol Rep, 2009, 22(2): 227232.
|
10. |
Klump B, Hsieh CJ, Dette S, et al. Promoter methylation of INK4a/ARF as detected in bilesignificance for the differential diagnosis in biliary disease [J]. Clin Cancer Res, 2003, 9(5): 17731778.
|
11. |
Koga Y, Kitajima Y, Miyoshi A, et al. Tumor progression through epigenetic gene silencing of O(6)methylguanineDNA methyltransferase in human biliary tract cancers [J]. Ann Surg Oncol, 2005, 12(5): 354363.
|
12. |
Hong SM, Choi J, Ryu K, et al. Promoter hypermethylation of the p16 gene and loss of its protein expression is correlated with tumor progression in extrahepatic bile duct carcinomas [J]. Arch Pathol Lab Med, 2006, 130(1): 3338.
|
13. |
Chinnasri P, Pairojkul C, Jearanaikoon P, et al. Preferentially different mechanisms of inactivation of 9p21 gene cluster in liver flukerelated cholangiocarcinoma [J]. Hum Pathol, 2009, 40(6): 817826.
|
14. |
Kim BH, Cho NY, Shin SH, et al. CpG island hypermethylation and repetitive DNA hypomethylation in premalignant lesion of extrahepatic cholangiocarcinoma [J]. Virchows Arch, 2009, 455(4): 343351.
|
15. |
Wong N, Li L, Tsang K, et al. Frequent loss of chromosome 3p and hypermethylation of RASSF1A in cholangiocarcinoma [J]. J Hepatol, 2002, 37(5): 633639.
|
16. |
Liu XF, Zhu SG, Zhang H, et al. The methylation status of the TMS1/ASC gene in cholangiocarcinoma and its clinical significance [J]. Hepatobiliary Pancreat Dis Int, 2006, 5(3): 449453.
|
17. |
Tischoff I, Markwarth A, Witzigmann H, et al. Allele loss and epigenetic inactivation of 3p21.3 in malignant liver tumors [J]. Int J Cancer, 2005, 115(5): 684689.
|
18. |
Abraham SC, Lee JH, Boitnott JK, et al. Microsatellite instability in intraductal papillary neoplasms of the biliary tract [J]. Mod Pathol, 2002, 15(12): 13091317.
|
19. |
Limpaiboon T, Khaenam P, Chinnasri P, et al.Promoter hypermethylation is a major event of hMLH1 gene inactivation in liver fluke related cholangiocarcinoma [J]. Cancer Lett, 2005, 217(2): 213219.
|
20. |
Isomoto H, Mott JL, Kobayashi S, et al. Sustained IL6/STAT3 signaling in cholangiocarcinoma cells due to SOCS3 epigenetic silencing [J]. Gastroenterology, 2007, 132(1): 384396.
|
21. |
McGinnis W, Krumlauf R. Homeobox genes and axial patterning [J]. Cell, 1992, 68(2): 283302.
|
22. |
Roberts DJ, Smith DM, Goff DJ, et al. Epithelialmesenchymal signaling during the regionalization of the chick gut [J]. Development, 1998, 125(15): 2791801.
|
23. |
Uchida T, Wada K, Akamatsu T, et al. A novel epidermal growth factorlike molecule containing two follistatin modules stimulates tyrosine phosphorylation of erbB4 in MKN28 gastric cancer cells [J]. Biochem Biophys Res Commun, 1999, 266(2): 593602.
|
24. |
Young J, Biden KG, Simms LA, et al. HPP1: a transmembrane proteinencoding gene commonly methylated in colorectal polyps and cancers [J]. Proc Natl Acad Sci USA, 2001, 98(1): 265270.
|
25. |
McCormick MB, Tamimi RM, Snider L, et al. NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family [J]. Mol Cell Biol, 1996, 16(10): 57925800.
|
26. |
Ogino S, Cantor M, Kawasaki T, et al. CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies [J]. Gut, 2006, 55(7): 10001006.
|
27. |
Kim BH, Cho NY, Choi M, et al. Methylation profiles of multiple CpG island loci in extrahepatic cholangiocarcinoma versus those of intrahepatic cholangiocarcinomas [J]. Arch Pathol Lab Med, 2007, 131(6): 923930.
|
28. |
Tannapfel A, Benicke M, Katalinic A, et al. Frequency of p16(INK4A) alterations and Kras mutations in intrahepatic cholangiocarcinoma of the liver [J]. Gut, 2000, 47(5): 721727.
|
29. |
Chen YJ, Tang QB, Zou SQ. Inactivation of RASSF1A, the tumor suppressor gene at 3p21.3 in extrahepatic cholangiocarcinoma [J]. World J Gastroenterol, 2005, 11(9): 13331338.
|
30. |
Hermann A, Gowher H, Jeltsch A. Biochemistry and biology of mammalian DNA methyltransferases[J]. Cell Mol Life Sci, 2004, 61(1920): 25712587.
|
31. |
Fang JY, Yang L, Zhu HY, et al. 5Aza2’deoxycitydine induces demethylation and upregulates transcription of p16INK4A gene in human gastric cancer cell lines [J]. Chin Med J (Engl), 2004, 117(1): 99103.
|
32. |
唐启彬, 孙华文, 邹声泉. 5氮2脱氧胞苷体内外抑制胆管癌细胞生长的研究 [J]. 中华普通外科杂志, 2004, 19(5): 295297.
|