• Department of General Surgery, The First Affiliated Hospital, Medical College, Xi’an Jiaotong University, Xi’an 710061, China;
Collagen; 　　TypeⅠ collagen; 　　Type Ⅲ collagen
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Objective　To analyze the contents of collagen type Ⅰ, type Ⅲ and the ratio of collagen type Ⅰ to collagen type Ⅲ in posterior rectus sheath of different person. Methods　One hundred and four tissues specimen of posterior rectus sheath were obtained during patients’ abdominal operation. The contents of collagen type Ⅰand type Ⅲ were detected by using immunohistochemistry methods. The differences of collagen contents between male and female, physical work group and non-physical work group, smoking group and non-smoking group were observed. The relationships between the contents of collagen and age, body mass index (BMI), and height were analyzed, respectively. Results　① The content of collagen typeⅠand the ratio of collagen type Ⅰ／Ⅲ were both lower in male than those in female （P lt;0.01）； there were no obvious differences in the content of collagen type Ⅲ and the total amount of collagen （P gt;0.05）. ② There were no differences between physical work group and non-physical work group with the amount and the ratio of collagens （P gt;0.05）. ③ When compared with non-smoking group, less collagen typeⅠ(P lt;0.01) and lower ratio of collagen Ⅰ／Ⅲ （P lt;0.05） were found in smoking group； but there was no difference with content of collagen Ⅲ（P gt;0.05）, as well as the total amount of collagen （P gt;0.05）. ④ The total amount of collagen, the content of collagen type Ⅰand the ratio of collagen Ⅰ／Ⅲ all decreased as age increases （r=0.341, 0.392, 0.212， P＜0.001, P lt;0.05）； no obvious change was observed in the content of collagen Ⅲ （r=0.089， P gt;0.05）. ⑤ The content and ratio of collagen had no obvious relationships with BMI and height （P gt;0.05）. Conclusion　Smoking, gender and age are all influential factors of the content and ratio of collagens in the tissue.

Citation： HE Xiangming,ZHANG Ruyuan,LIU Hao,FAN Lin,ZHAO Wei,WANG Guanghui. Initial Study on Contents of TypeⅠand Type Ⅲ Collagen in Posterior Rectus Sheath in People of Different Groups. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2008, 15(6): 440-443. doi: Copy