• Liver Transplantation Division, The First People’s Hospital of Kunming City and The Affiliated Ganmei Hospital of Kunming Medical College, Kunming 650011, ChinaCorresponding Author: LI Li, E-mail: ynkmlili@yahoo.com.cn;
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Objective  To report the progression of breviscapine’s protective effect to hepatic ischemia-reperfusion injury.
Methods  Pertinent literatures and journal articles published in recent years were reviewed, and the progression of breviscapine protecting hepatic ischemia-reperfusion injury in the experimental and clinical research were analyzed and summarized.
Results  The role of breviscapine is considerable extensive. It can protect hepatic ischemia-reperfusion injury by anti-oxyradical and anti-lipid peroxidation, inhibiting mitochondrial damage, intracellular calcium overload, intra-thromboxane and apoptosis, improving microcirculation, and so on.
Conclusion  Breviscapine plays a protective role in hepatic ischemia-reperfusion injury, and it will be of great value to application and research.

Citation: WANG Zhikang,LI Li. Progression of Breviscapine Protecting Hepatic Ischemia-Reperfusion Injury. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2008, 15(9): 708-710. doi: Copy