目的探讨哈乐预防腹部手术后尿潴留的临床价值。
方法哈乐组于拔尿管前1 d开始用哈乐0.2 mg,1次/d,3~5 d; 对照组未予特殊药物治疗。比较2组的尿潴留发生率、尿路感染发生率、住院时间和副作用。
结果哈乐组未发生尿潴留,对照组尿潴留发生率为28%,差异有统计学意义(P<0.05)。哈乐组无一例发生尿路感染,对照组有5例(20%),2组间差异无统计学意义(P gt;0.05)。哈乐组术后平均住院时间为(10.7±3.3) d,对照组为(11.6±3.0) d,2组间差异亦无统计学意义(P gt;0.05)。
结论哈乐可明显减少尿潴留的发生率,是预防腹部手术后尿潴留的有效药物。
Citation:
张明鸣,伍晓汀,蒋汉卿,庄文,杨纲. Clinical Application of Harnal in Prevention of Urinary Retention after Abdominal Operation. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2006, 13(3): 331-332. doi:
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- 1. Expert Opin Pharmacother, 2004; 5(1)∶151.
- 2. Lee E, Lee C. Clinical comparison of selective and nonselective alpha 1Aadrenoreceptor antagonists in benign prostatic hyperplasia: studies on tamsulosin in a fixed dose and terazosin in increasing doses [J]. Br J Urol, 1997; 80(4)∶606.
- 3. Patel R, Fiske J, Lepor H. Tamsulosin reduces the incidence of acute urinary retention following early removal of the urinary catheter after radical retropubic prostatectomy [J]. Urology, 2003; 62(2)∶287.
- 4. 杨竹, 钟铃, 胡丽娜. 坦索罗辛在妇科手术后尿潴留中的作用 [J]. 临床泌尿外科杂志, 2002; 17(3)∶119.
- 5. Michel MC, de la Rosette JJ. Efficacy and safety of tamsulosin in the treatment of urological diseases [J].