• Cardiovascular Instiute & Fu Wai Hospital; Chinese Academy of medical Science; Beijing 100037; China;
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The re-evaluation of the effectiveness of new drugs is of great importance when they are in post-market for there exist some limitations in clinical trials before these drugs are put on the market. The large sample multi-centre randomized controlled trial is the best method of re-evaluation of the effectiveness of new drugs. It could appropriately evaluate not only the large-term efficacy and safety of drugs, but the treatment effect on the survival state and its complications as well. This method will also lead to a great social  amp; economic benefit.

Citation: WANG Wen. The best method of re-evaluation of effectiveness of drugs--the large sample, multi-center, randomized controlled trial. Chinese Journal of Evidence-Based Medicine, 2002, 02(3): 145-148. doi: Copy