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"中央型肺癌" 4 results
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目的 总结肺动脉、支气管成形肺叶切除术治疗中央型肺癌的临床经验,探讨手术的应用指征及方法,以提高手术疗效和患者的生存率。 方法 自1995年1月至2005年12月,对64例中央型肺癌患者施行肺动脉、支气管成形肺叶切除术,包括袖式肺叶切除术21例,支气管楔形肺叶切除术11例,支气管、动脉双袖式肺叶切除术2例,肺动脉成形(楔形+线形)肺叶切除术30例。 结果 全组无手术死亡。术后发生并发症12例(18.75%),其中肺不张7例次,心律失常7例次,有肺不张、心律失常和肺部感染2例。术后随访64例,随访时间1~5年,随访期间死亡9例,死亡原因为肿瘤远处转移,包括脑、纵隔、颈部淋巴结和全身骨转移。术后1、3、5年的生存率分别为88%、58%和42%,中位生存时间为45.76个月。N0患者(21例) 1、3、5年生存率分别为93%、82%和56%;N1患者(28例)为75%、56%和39%;N2患者(15例)为55%、21%和12% (Plt;0.01)。 结论 肺动脉、支气管成形肺叶切除术扩大了肺癌患者的手术指征,减少了因肺动脉受侵犯而行全肺切除术,提高了患者术后的生存质量。对该类手术,淋巴结转移分期仍然是影响术后生存率的主要因素。
Release date:2016-08-30 06:10
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ObjectiveTo discuss the diagnostic value of multi-slice spiral CT for bronchial mucoid impaction in early central-type carcinoma of lung.
MethodsWe used multi-planar reformat, maximum intensity projection and minimum intensity projection to observe the characteristics of 15 patients with bronchial mucoid impaction in early central-type carcinoma of lung treated between March 2010 and October 2013. The characteristics included location, shape and enhanced performance of the tumor and the bronchial mucoid impaction. All the cases were confi rmed by operation or pathology.
ResultsAmong the 15 cases, 12 were squamous cell carcinoma and 3 adenocarcinoma; 8 occurred on the right and 7 on the left. All the tumors showed equal density and were enhanced moderately. Bronchial mucoid impaction showed low density, no enhancement, accompanied bronchiectasis and occurred in bronchi which were far from the tumor, and there were 9 cases of strip, 5 of fabrication, and 1 of nodositas or cystic carcinoma.
ConclusionThe location and shape of tumor and bronchial mucoid impaction are displayed clearly by multi-slice spiral CT and enhancement scanning can differentiate tumor from bronchial mucoid impaction. Multi-slice spiral CT has important diagnostic value in bronchial mucoid impaction of primary lung cancer in its early stage.
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目的
探讨血管介入联合气道介入治疗在晚期中央型肺癌中心气道重度狭窄的临床应用价值。
方法
32 例晚期中央型肺癌中心气道重度狭窄患者于局麻下接受血管介入支气管动脉灌注化疗(BAC)和支气管动脉栓塞(BAE)肺癌供血血管介入治疗,然后在全麻下经电子支气管镜行冷冻切除、高频电、氩气刀(APC)、支架置入等气道介入治疗。测定患者治疗前及治疗后 2 周的气促指数、气道管径、FEV1%pred、Karnofsky 评分(KPS)、6 分钟步行距离(6MWD),以及血清鳞状细胞癌相关抗原(SCCA)、非小细胞肺癌相关抗原细胞角蛋白 19 片段抗原 21-1(CYFRA21-1)、神经元烯醇化酶(NSE)及癌胚抗原(CEA)水平。比较各指标治疗前后的变化,观察疗效及并发症。
结果
32 例患者均顺利完成 BAC+BAE 血管介入治疗联合气道介入治疗,临床有效率为 96.9%。气道介入麻醉方式:喉罩全麻 3 例,气管插管全麻 29 例。气道介入治疗方法:高频电烧灼治疗 28 例,电圈套 8 例,APC 治疗 16 例,冷冻切除治疗 26 例,气道支架置入 5 例。所有患者治疗后气促指数、气道管径、FEV1%pred、KPS 及 6MWD 各指标与治疗前比较均有显著改善(P 均<0.05),血清 SCCA、CYFRA21-1、NSE、CEA 水平较治疗前显著下降(P 均<0.05)。治疗过程中出现恶心呕吐 2 例,无气道大出血病例,无严重及致死性并发症。
结论
血管介入联合气道介入治疗晚期中央型肺癌中心气道重度狭窄具有微创、气道出血少、近期疗效确切的优势,具有很好的临床应用价值。
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Release date:2018-01-31 02:46
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