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find Keyword "乳腺癌改良根治术" 5 results
  • 康复新液与湿润烧伤膏治疗乳腺癌改良根治术后皮肤溃疡的疗效比较

    目的观察康复新液和湿润烧伤膏治疗乳腺癌改良根治术后皮肤溃疡的临床疗效,为乳腺癌术后进一步治疗提供指导。 方法将2009年3月-2013年3月行乳腺癌改良根治术后发生皮肤溃疡的122例患者,按入院的奇偶日期分为试验组和对照组,每组61例。试验组患者术后第3天开始口服康复新液,3次/d,10 mL/次,同时用康复新液湿敷溃疡处,1次/d;对照组患者则涂抹湿润烧伤膏,凡士林纱布置于创面,1次/d,对两组患者治疗20、30、40 d的疗效进行比较。 结果治疗40 d时,试验组总有效率100%,对照组98%,两组比较差异无统计学意义(P>0.05);试验组愈合时间(19.56±3.79)d,对照组(33.26±4.55)d,两组比较差异有统计学意义(P<0.05)。 结论两种药物治疗乳腺癌改良根治术后皮肤溃疡均有明显效果,但康复新液的愈合速度更快,优于湿润烧伤膏。

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  • Comparison of Efficacy Study of Simple Negative Pressure Drainage and It Combined with Chest Compression Bandaging after Radical Mastectomy for Breast Cancer

    ObjectiveTo compare the differences in preventing subcutaneous effusion, skin flap necrosis, and patient comfort between simple negative pressure drainage and negative pressure drainage combined with chest compression bandaging after radical mastectomy for breast cancer. MethodsOne hundred and ninety-six patients underwent radical mastectomy for breast cancer from January 2010 to December 2012 in this hospital were collected.The simple negative pressure drainage (SNPD group, n=84) and negative pressure drainage combined with chest compression bandaging (NPD+CB group, n=112) after radical mastectomy for breast cancer were used to prevent postoperative subcutaneous effusion.The postoperative complications, postoperative 3 d drainage volume, and patient comfort were compared in two groups. ResultsOne hundred and ninety-six patients with breast cancer were females.The differences of general clinical data were not statistically significant in two groups (P > 0.05).The differences of chest wall mean extubation time, axillary mean extubation time, postoperative 3 d mean drainage volume, and incidences of subcutaneous effusion and skin flap necrosis were not statistically significant in two groups (P > 0.05).The rate of comfort satisfactory in the SNPD group was significantly higher than that in the NPD+CB group [76.2%(16/84) versus 22.3%(25/112), P < 0.001].The chemotherapy was not affected after operation in two groups. ConclusionsComparing with negative pressure drainage combined with chest compression bandaging, simple negative pressure drainage do not increase postoperative subcutaneous effusion and skin flap necrosis, but it greatly improves the patients satisfactory rate.

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  • Clinical Efficacy of Immediate Breast Reconstruction with Extended Latissimus Dorsi Musculocutaneous Flap after nipple and areola Sparing modified radical mastectomy for patients with Early-Middle Breast Cancer

    ObjectiveTo explore the clinical efficacy of immediate breast reconstruction with extended latissimus dorsi musculocutaneous flap after nipple and areola sparing modified radical mastectomy for patients with early-middle breast cancer. MethodsSixty patients diagnosed with early-middle breast cancer by needle biopsy from November 2009 to October 2012 in this hospital were divided into two groups according to the surgical method.The breast reconstruction group (30 cases) were performed immediate breast reconstruction with extended latissimus dorsi musculocutaneous flap after nipple and areola sparing modified radical mastectomy, the control group (30 cases) were performed traditional modified radical mastectomy.The postoperative complications, clinical efficacy, quality of life, and recurrence and metastasis were compared in two groups. Results①The ipsilateral breast was completely missing in the control group.The aesthetic effect in the breast reconstruction group was satisfactory including excellent in 22 patients, good in 7 patients, general in 1 patient.②The rates of flaps effusion, flap necrosis, and affectied limb activity limitation had no significant differences in two groups (P > 0.05).The wound healing time, operation area drainage time, hospital stay, and post-operative chemotherapy start time all had no significant differences in two groups (P > 0.05).③The frequency of psycho-logical pressure (inferiority/anxiety/fear) and rate of un-satisfaction of secondary sexual characteristics (body/curve) in the breast reconstruction group were lower than those in the control group (P < 0.001).The rate of social interaction fitness in the breast reconstruction group was higher than that in the control group (P < 0.001).④The following-up time was 12 to 38 months with an average 25 months, one case died because of brain metastasis in the control group, the rest 59 patients had no local recurrence and distant metastasis. ConclusionsThe immediate breast reconstruction with exte-nded latissimus dorsi musculocutaneous flap after nipple and areola sparing modified radical mastectomy can cure cancer on the basis of satisfactory cosmetic results of breast, excellent quality of life of patients, and fewer surgical complica-tions.It does not affect postoperative adjuvant radiochemotherapy and short-and long-term efficacy for breast cancer.

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  • The preventive effectiveness of air pressure pump combined with the microwave physiotherapy on arm lymphedema after modified radical mastectomy for breast cancer

    Objective To explore the preventive effectiveness of early physiotherapy on arm lymphedema after modified radical mastectomy for breast cancer. Methods A total of 206 patients who underwent modified radical mastectomy for breast cancer in The First Affiliated Hospital of Henan University from June 2014 to June 2016, enrolled in this randomized controlled clinical trial. Then these patients were randomly divided into intervention group and control group equally. Patients in the control group received routine treatment, and the patients in the intervention group began to use the air pressure pump combined with the microwave physiotherapy on the second day after the radical surgery. The incidences of limb lymphedema in 6 months and 1 year after operation between the 2 groups were compared, and the influencing factors of arm lymphedema were explored. Results The clinical data of 195 patients were analyzed at end, including 99 patients of the intervention group and 96 patients of the control group. ① There were statistical significance in the incidences of arm lymphedema in 6 months and 1 year after operation between the 2 groups (P<0.05), that incidences of arm lymphedema in the intervention group were both lower than those of the control group at the2 time points [6 months after operation: 2.0% (2/99)vs. 9.4% (9/96); 1 year after operation: 5.1% (5/99) vs. 17.7% (17/96)]. ② The results of non-conditional logistic regression analysis shown that, age (OR=1.45, P=0.008), tumor location (OR=1.72, P<0.001), TNM stage (OR=2.01, P=0.033), the number of invasive axillary lymph nodes (OR=1.15, P=0.005), and postoperative radiotherapy (OR=1.23, P=0.016) were the influencing factors of arm lymphedema after modified radical mastectomy for breast cancer, patients with age older than 60 years, tumor position at the outside area, stage Ⅲ of TNM, the number of invasive axillary lymph nodes >5, and patients received radiotherapy after operation had high risk of arm lymphedema. Conclusion Early physiotherapy can effectively prevent the occurrence of arm lymphedema after modified radical mastectomy for breast cancer, and early physiotherapy should be performed for patients with high risk of arm lymphedema.

    Release date:2018-02-05 01:53 Export PDF Favorites Scan
  • 负压封闭引流在乳腺癌改良根治术后腋窝引流中的应用价值

    目的评价负压封闭引流(VSD)在乳腺癌改良根治术后腋窝引流中的应用效果。 方法收集 2017 年 1 月至 2018 年 2 月期间达州市中心医院乳腺甲状腺外科收治的 128 例行乳腺癌改良根治术患者的临床资料(均为女性),其中胸壁及腋窝均使用普通硅胶管引流患者 60 例(对照组),胸壁使用普通硅胶管而腋窝使用去除吸附泡沫材料的 VSD 装置患者 68 例(观察组),比较 2 组患者的术后腋窝拔管时间以及腋窝皮瓣感染、腋窝积液和皮瓣坏死及切口愈合情况。 结果与对照组比较,观察组的腋窝拔管时间明显更早(Z=–3.340,P=0.001),腋窝皮瓣感染率(χ2=4.486,P=0.034)和腋窝积液率(χ2=5.901,P=0.015)更低,切口甲级愈合率更高(χ2=11.715,P=0.001),而 2 组术后腋窝皮瓣坏死率比较差异无统计学意义(χ2=0.483,P=0.487)。 结论乳腺癌改良根治术后腋窝使用 VSD 能降低患者术后腋窝并发症的发生率。

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