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find Keyword "乳腺良性肿瘤" 3 results
  • Discussion on Relation Between Plasma Homocysteine and Breast Cancer

    Objective To explore the correlation between homocysteine (Hcy) level and the risk of breast cancer,and try to find a new method to reduce the risk factors and benefit for treatment of breast cancer. Methods From January2010 to December 2012, 245 cases of breast cancer (breast cancer group), 109 cases of benign breast tumor (benign breast tumor group), and 78 cases of healthy women (healthy control group) in the Sichuan Provincial People’s Hospital, who were in accordance with the inclusion criteria, were analyzed retrospectively. The difference of Hcy level was compared among three groups. Meanwhile the relation between Hcy level and patients’s age, blood glucose, serum creatinine, estrogen receptor (ER), progesterone receptor (PR), Ki-67 (%), tumor diameter, or axillary lymph node status was analyzed.Results ① The Hcy level was significantly different among the breast cancer group, benign breast tumor group, and healthy control group (P<0.001). The Hcy level of the breast cancer group was significantly higher than those of the benignbreast tumor group (P<0.001) or healthy control group (P<0.001), but the Hcy level was not significantly different bet-ween the benign breast tumor group and healthy control group (P=0.082) . ② The Hcy levels of different types of the breastcancer (type of Luminal A, Luminal B, Her-2, and triple negative) were significantly higher than those of the benign breast tumor group (except for Her-2 type, P<0.05) or healthy control group (P<0.05). ③Plasma Hcy level of the patients with benign and malignant breast tumor was positively correlated with age (r=0.197, P=0.004) or serum creatinine level (r=0.381, P<0.001), but not correlated with blood glucose (r=0.023, P=0.668). ④Plasma Hcy level of the patients with malignant breast tumor was positively correlated with age (r=0.267, P=0.007) or serum creatinine level (r=0.341, P<0.001), but not correlated with blood glucose (r=-0.005, P=0.935), tumor diameter (r=-0.049, P=0.443), axillary lymph node status (r=-0.006, P=0.921), or Ki-67 (%) (rs=-0.029, P=0.650). Conclusions Plasma Hcy level of breast cancer patient is abnormally elevated, and it may have some relation with the occurrence of breast cancer.

    Release date:2016-09-08 10:35 Export PDF Favorites Scan
  • Investigate The Relationship Between Abnormal Thyroid Function and Benign or Malignant Breast Tumors

    ObjectiveTo investigate the correlation between abnormal thyroid function and benign or malignant breast tumors. MethodsThe contents of free iodine three original acid (FT3), three iodine original acid (T3), thyroxine (T4), free thyroxine (FT4), thyroid-stimulating hormone (TSH), anti-thyroglobulin antibodies (Anti-TG), and antithyroid peroxidase antibody (Anti-TPO) were detected by chemiluminescence method in 563 patients with benign breast neoplasms, 87 patients with breast cancer, and 123 health examination population. ResultsT3 and T4 levels in patients with breast cancer were lower than those of normal control group and benign tumor group (P < 0.05). However, there were no significant difference in the levels of FT3, FT4, and TSH between the 3 groups (P > 0.05). The positive rates of Anti-TPO and Anti-TG were higher than those of benign group and normal group (P < 0.001). T3 and T4 levels in patients with breast cancer were not related to the expression of ER and PR, in Her-2 negative expression and lymph node metastasis were relatively low (P < 0.05). ConclusionThe decrease of contents of T3 and T4, and the positive expressions of Anti-TPO and Anti-TG may provide a basis for predicting the incidence of breast cancer.

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  • 留置针引流在乳腺良性肿瘤开放手术的应用效果分析

    目的分析乳腺良性肿瘤开放手术后创腔使用留置针引流的临床疗效。方法回顾性收集2018年7月至2021年6月期间四川大学华西医院乳腺外科收治的109例乳腺良性肿瘤患者(手术创腔放置留置针引流)的临床资料,评价患者的住院时间、留置针放置时间、临床效果、术后相关并发症及美容效果。结果109例放置留置针引流的乳腺良性肿瘤患者均行日间手术,住院时间均为1 d,术后留置针放置时间为(2.6±0.5)d,未出现切口感染、积液、脂肪液化、出血等并发症。患者术后乳房外形满意,活动不受影响。结论应用留置针引流乳腺良性肿瘤患者的术后创腔,操作简单,临床疗效好,患者满意度高,外形影响小。

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