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find Keyword "代谢性疾病" 3 results
  • 内毒素诱发胰岛素抵抗机制的研究进展

    内毒素是革兰阴性菌细胞壁的成分之一,其化学结构为脂多糖。胰岛素抵抗在肥胖、代谢综合征、心血管疾病、2 型糖尿病及其并发症等疾病的病理病程中起了重要的作用。现有研究认为肥胖及相关代谢性疾病是慢性低度炎症性疾病,长期慢性炎症可以削弱胰岛素的生物效应。肠道菌群结构紊乱或肠黏膜屏障受损,机体循环系统中内毒素水平增加,诱发慢性低度炎症可致宿主胰岛素抵抗或肥胖。该文综述了近年来内毒素诱发胰岛素抵抗及相关代谢性疾病机制的研究进展。

    Release date:2017-11-24 10:58 Export PDF Favorites Scan
  • Current status and future perspectives of stomach-targeted endoscopic bariatrics

    Endoscopic bariatric treatment (EBT) is an effective method for the treatment of obesity. The principle of weight loss is similar to metabolic bariatric surgery. It can be classified as a food restriction (stomach-targeted) and malabsorption (small intestine-targeted). At present, a lot of EBT devices had been cleared by the US Food and Drug Administration to treat obesity, while the EBT in China lagged behind Western countries. Hence, we reviewed the current stomach-targeted EBT, aiming to provide a reference for the supplement of obesity treatment methods and the development of EBT in China.

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  • Relationship between branched-chain amino acids and aging and health of the elderly

    Skeletal muscle and metabolic function are important factors affecting the health status of the elderly. Branched-chain amino acids (BCAA) can improve muscle recovery, reduce muscle soreness after exercise, and BCAA can also enhance metabolic health, helping to regulate blood sugar levels and improve insulin sensitivity in the elderly. In addition, BCAA can improve cognitive function, reducing the risk of age-related cognitive decline. This article reviews the relationship between BCAA and aging, skeletal muscle, and metabolic diseases, explaining how BCAA can support and promote muscle mass and function in the elderly, as well as have a positive impact on metabolic health and cognitive function.

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