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find Keyword "低流量" 5 results
  • Changes of pulmonary surfactant activity after deep hypothermic cardiopulmonary bypass in infants

    Objective To compare the changes between deep hypothermic circulatory arrest (DHCA) with deep hypothermic low flow (DHLF) cardiopulmonary bypass (CPB) on pulmonary surfactant (PS) activity in infants with congenital heart disease. Methods Twenty infants with ventricular septum defect and pulmonary hypertension were assigned to either DHCA group or DHLF group according to the CPB methods respectively. Measurements of saturated phosphatidylcholine /total phospholipids (SatPC /TPL), saturated phosphatidylcholine/ total protein (SatPC/TP) and static pulmonary compliance were performed before institution of CPB, 5 minutes after cessation of CPB and 2 hours. Results The length of ICU stay in DHLA group was significantly longer ( P lt;0 05) than that in DHCA group. SatPC/TPL, SatPC/TP and static pulmonary compliance in DHLF group were significantly lower compared with DHCA group ( P lt;0.01). Conclusion DHLF could lower the PS activity level significantly as compared with DHCA in infants with congenital heart disease.

    Release date:2016-08-30 06:27 Export PDF Favorites Scan
  • 心脏手术深低温低流量灌注不同血气管理对婴幼儿脑保护的影响

    摘要 目的 在深低温低流量灌注模式下,观察快速降温期应用不同稳态血气管理对婴幼儿脑功能的影响。方法 将20例法洛四联症患者随机分为pH稳态和alpha稳态两组,并根据不同时间点、低流量和血气管理方案随机平均分层行析因分析。脑功能监测为:生化指标、脑温、脑电图、智商等。结果 应用pH稳态的脑部温差较应用 alpha稳态低;复温末alpha稳态组中低流量25ml/kgmin-1乳酸含量最高;术后24小时alpha稳态组中低流量25ml/kgmin-1神经元特异性烯醇酶含量最高;术后 4天脑电图和术后 2个月智商两种稳态组间差别无显著性意义。结论 深低温低流量灌注快速降温期应用pH稳态进行血气管理可起到更好的脑保护作用。

    Release date:2016-08-30 06:33 Export PDF Favorites Scan
  • 深低温下肺动脉取栓术的体外循环管理

    目的 总结在深低温下行肺动脉取栓术体外循环管理的经验。方法 7例急性肺栓塞患者均在深低温低流量和深低温停循环下行肺动脉取栓术,并通过间断恢复血流,延迟复温,药物处理等技术,保护患者的心、脑、肺、肾等功能。结果 1例由于体外循环时间较长(335分钟),且心功能较差,静脉血氧饱和度不能有效的维持,脱机困难,使用了体外膜肺支持,最终因多器官功能衰竭而死亡。1例因肺水肿施行二次肺动脉环缩术后,肺水肿明显改善;其他患者术后恢复顺利。结论 在深低温体外循环下行肺动脉取栓术是安全有效的方法。

    Release date:2016-08-30 06:33 Export PDF Favorites Scan
  • A Clinical Comparison Between Low Flow Sevoflurane TargetControlled and TCI of Propofol

    目的:观察七氟醚靶控用于低流量吸入麻醉维持的临床规律及血流动力学变化,寻求靶控下的药物量化指标。方法:选择60例20~60岁手术患者,随机分2组每组30例:P组(丙泊酚)常规实施全凭静脉TCI靶控麻醉;S组(七氟醚),实施低流量七氟醚靶控吸入麻醉(BIS值40)。分别记录诱导前(T1),插管后5(T2)、15(T3)、30(T4)45(T5)、60(T6)、90(T7)、120(T8)min时的、MBP、HR、;Sev组患者加记各个时点的七氟醚IT、ET的MAC值。结果:T2点两组均比T1 降低(Plt;0.05),S 组高于P组(Plt;0.05),两组比较T3至T7无显著性差异(Pgt;0.05);S 组T3 至T7 各点ET值无统计学差异,ET%:2.46,约1.4 MAC。结论:(1)七氟醚诱导较静脉麻醉诱导患者血流动力学稳定,(2)低流量七氟醚靶控吸入麻醉维持平稳,调控简便,效果良好。

    Release date:2016-09-08 10:01 Export PDF Favorites Scan
  • Clinical Effects of Non-humidified versus Humidified Low-to-moderate Flow Oxygen Inhalation Therapy via Nasal Cannula: A Systematic Review

    ObjectiveTo systematically review the clinical effects of non-humidified versus humidified low-to-moderate flow oxygen inhalation therapy via nasal cannula. MethodsRandomized controlled trials (RCTs), clinical controlled trials (CCTs) and cross-over studies about the clinical effects of non-humidified versus humidified low-to-moderate flow nasal cannula oxygen inhalation therapy in hospitalized adult patients were searched in The Cochrane Library (Issue 3, 2016), The Joanna Briggs Institute Evidence Based Practice (EBP) Database, EMbase, PubMed, Web of Science, CBM, CNKI, VIP and WanFang Data from inception to March 2016. Three reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Then meta-analysis was performed using RevMan 5.3 software. ResultsA total of nine RCTs and three CCTs involving 3 756 patients were finally included. The results of meta-analysis indicated that: non-humidified was superior to humidified oxygen therapy in reducing bacterial contamination of oxygen apparatus (P < 0.05) and the time of daily replacement of sterile water oxygen humidifier bottles (P < 0.05), while the two groups were alike in relieving nasal dryness (RR=1.08, 95%CI 0.91 to 1.29, P=0.37), nasal bleeding (RR=1.17, 95%CI 0.66 to 2.08, P=0.59) and discomfort (RR=0.80, 95%CI 0.56 to 1.14, P=0.22). ConclusionCurrent evidence indicates that there is no significant difference between non-humidified and humidified low-to-moderate flow nasal cannula oxygen inhalation therapy in relieving patients' nasal dryness, nasal bleeding and discomfort. But non-humidified oxygen therapy can reduce bacterial contamination of oxygen apparatus, simplify the operation procedures and lessen nurses' operation time.

    Release date:2016-10-02 04:54 Export PDF Favorites Scan
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