目的 探讨和对比无针缝合器与传统的二期针线缝合和蝶形胶布拉拢对感染切口的闭合疗效。方法 对49例肝胆术后切口感染患者，待感染切口引流物明显减少、创面有健康肉芽生长时，应用立辰无针缝合器逐步闭合切口。另81例肝胆术后切口感染患者分别采用蝶形胶布拉拢或二期传统针线缝合，对比3组患者切口自换药开始至切口拆线的愈合时间。结果 无针缝合治疗组的愈合时间为（23.0±6.5）d，明显短于蝶形胶布拉拢组的（31.0±10.4）d和二期传统针线缝合组的（34.0±14.1）d（P＜0.05）。蝶形胶布拉拢组与二期传统针线缝合组愈合时间差异无统计学意义（P＞0.05）。结论 采用无针缝合器治疗感染切口可在引流换药的同时逐步闭合切口，促进其早期愈合。
Objective To evaluate the clinical effect of minimally invasive aortic valve replacement with Perceval sutureless aortic bioprosthesis in upper ministernotomy or right anterior thoracotomy. MethodsFrom March to November 2022, the patients with simple aortic valve disease were enrolled in the Department of Cardiovascular Surgery of West China Hospital, Sichuan University. After preoperative evaluation, Perceval sutureless bioprosthesis was successfully used to perform aortic valve replacement through the upper ministernotomy or right anterior thoracotomy. The perioperative clinical data and ultrasonic measurement data of all patients were recorded. ResultsA total of 5 patients with simple aortic valve disease were included, including 3 females and 2 males, with a mean age of 71.2 years. Perceval sutureless bioprosthesis was successfully implanted in 5 patients, with a success rate of 100%. There were 3 patients receiving upper ministernotomy and 2 patients receiving right anterior thoracotomy. Two patients underwent ascending aortic plasty at the same time. The mean cardiopulmonary bypass time was 61.0 min, and aortic cross-clamping time was 32.2 min. All patients were discharged successfully without perivalvular leakage, atrioventricular block or stroke. ConclusionThe implantation method of Perceval sutureless bioprosthesis is simple, which can effectively reduce the perioperative risk by shortening the overall operation time, cardiopulmonary bypass time and aortic cross-clamping time. At the same time, its clinical application has promoted the development and popularization of minimally invasive aortic valve replacement, which together with Perceval sutureless bioprosthesis effectively combinates surgical effect and minimally invasive treatment, and has a good clinical application prospect because of its reliable safety and effectiveness.