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find Author "冷英杰" 2 results
  • PiCCO联合腹内压实时监测在危重患者中的应用及相关性分析

    目的探讨同步观察脉搏指示连续心排出量(PiCCO)和连续腹内压监测技术在ICU危重患者中的联合应用, 对二者的相关性进行分析。 方法我院普外科ICU病房2014年1月至2015年6月收治并同时进行了PiCCO和腹内压实时监测的危重患者共8例, 通过建立PiCCO监测通道以及腹腔内低顺应性毛细测压管, 记录患者进入ICU病房3 d内每隔8 h同步监测PiCCO所测得的连续心排出量(PCCO)以及腹腔内直接测压法所测得的腹内压。 结果8例患者术后3 d内每8 h同步记录的PCCO及腹内压共72个记录点的数据进行排除患者因素的偏相关性分析, 所得相关系数R=-0.682(P < 0.001)。 结论危重患者的腹内压与PCCO间存在显著的负相关性, 同步监测有利于更全面地掌握患者病情, 值得在临床中进一步应用和探索。

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  • Characteristics and influencing factors of postoperative weight change in patients with esophageal cancer: A prospective longitudinal study

    ObjectiveTo longitudinally investigate the characteristics of postoperative weight changes in patients with esophageal cancer and analyze its influencing factors, which can provide certain guidance for nutritional intervention in patients with esophageal cancer. MethodsPatients with esophageal cancer who underwent surgical treatment at the Sichuan Cancer Hospital from December 2020 to February 2022 were prospectively included. The general information questionnaire and body composition analyzer were used to longitudinally investigate the patients’ weight and body composition before surgery (T0), 1 month after surgery (T1), 3 months after surgery (T2) and 6 months after surgery (T3), and the change characteristics were analyzed. The generalized estimating equation was used to analyze the influencing factors for postoperative weight changes in patients with esophageal cancer. ResultsA total of 130 patients were enrolled, including 110 males and 20 females, aged 42-79 (63.33±8.16) years. The weight and body composition of patients with esophageal cancer showed a continuous slow downward trend within 6 months after surgery. The weight loss rate of patients at 1, 3, and 6 months after surgery was 5.10%, 7.76%, and 9.86%, respectively. At the same time, the analysis results of the influencing factors for postoperative weight showed that patients with the following characteristics had more weight loss: female (β=−7.703, P=0.001), ≥60 years (β=−3.657, P=0.010), smoking (β=4.622, P=0.010), low tumor differentiation degree (β=4.314, P=0.039), and high frequency of eating (β=−3.400, P=0.008). ConclusionWeight loss is an important health problem for patients with esophageal cancer after surgery, and patients have a continuous downward trend in weight within 6 months after surgery. Medical staff should pay special attention to the patients who are female, ≥60 years, having smoking history and low tumor differentiation degree.

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