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find Author "刘巾男" 2 results
  • 微小RNA与前列腺癌的研究进展

    【摘要】 微小RNA(microRNA,miRNA)是近年来发现的一类长度为18~26个核苷酸的非编码小分子RNA。它主要通过与靶标基因3’-UTR的完全或不完全配对,降解靶标基因mRNA或抑制其翻译,从而参与调控生命活动,影响肿瘤的发生和发展。目前研究发现,大量miRNA的表达变化与前列腺癌的发生发展相关,了解这些miRNA的表达规律和作用机制对深入探讨前列腺癌的发病机制、研究新的诊断和治疗手段意义重大。综述主要介绍近年来miRNA与前列腺癌发生的关系及对其诊治的研究进展。

    Release date:2016-09-08 09:24 Export PDF Favorites Scan
  • Fundus Analysis of Familial Exudative Vitreoretinopathy

    ObjectiveTo observe and explore the fundus characteristics and fundus fluorescein angiography of familial exudative vitreoretinopathy (FEVR) in different stages. MethodsA total of 15 patients (23 eyes) diagnosed as FEVR in the West China Hospital of Sichuan University from January 2007 to November 2013 were included. Clinical data and reports of fundus exams and fundus fluorescein angiography (FFA) were retrospectively analyzed. ResultsOne eye (4.35%) was classified as stage Ⅰ, 10 eyes (43.48%) were classified as stage Ⅱ, 8 eyes (34.78%) were classified as stage Ⅲ, and 1 eye (4.35%) and 3 eyes (13.04%) were classified as stage Ⅳ and V, respectively. The outcomes of fundus exams showed that the number of peripheral retinal blood vessels increased, and vessels straightened as well as narrowed, especially in the temporal area. FFA showed blood vessels suddenly shut in the equatorial retina and peripheral non-perfusion areas were observed. ConclusionTypical fundus characteristics and fundus fluorescein angiography changes of FEVR can be observed in different stages. Comprehensive fundus exams and family history are helpful to confirm relevant diagnosis.

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