west china medical publishers
Author
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Author "刘相燕" 2 results
  • Advances in the treatment of chest wall surgical diseases

    Chest wall surgery used to be a subspecialty of traditional thoracic surgery, which has an ancient history of research and clinical practice. It has gradually become an independent professional field in recent years. With the change of concept and the progress of interdisciplines, we have deepened our understanding of related diseases, and the treatment of chest wall surgical diseases has also acquired new characteristics. This article reviews the progress in the treatment of chest wall surgical diseases including chest wall trauma, chest wall deformity, chest wall tumor, chest wall infection and chest wall defect from the perspective of chest wall surgery.

    Release date: Export PDF Favorites Scan
  • 非小细胞肺癌隐匿性淋巴结转移的基因诊断

    目的 探讨非小细胞肺癌(NSCLC)隐匿性纵隔淋巴结转移病灶的基因诊断方法. 方法 应用逆转录聚合酶链反应法(RT-PCR), 检测30例NSCLC患者(实验组,N0,Ⅰa~Ⅱb期)手术后病理诊断为阴性的138枚纵隔淋巴结中MUC1基因mRNA的表达,并用30枚肺良性疾病的局部淋巴结作阴性对照(阴性对照组),用30枚经病理证实有转移的NSCLC纵隔淋巴结作阳性对照(阳性对照组).对患者进行随访,用χ2检验比较MUC1基因mRNA阳性者和阴性者的预后差别. 结果 阴性对照组30枚肺良性疾病的局部淋巴结均无MUC1基因mRNA表达(特异性为100%),阳性对照组30枚经病理证实有转移癌的肺癌纵隔淋巴结中26枚检测到MUC1基因mRNA的表达(敏感性为87%).实验组9例患者的11枚淋巴结中检测到MUC1基因mRNA表达(检出率8.0%),患者的分期上调为Ⅲa期.实验组中MUC1基因mRNA阳性患者预后不良,随访2年有4例复发、转移或死亡;MUC1基因mRNA阴性者仅1例转移(P<0.05 ). 结论 应用RT-PCR法检测纵隔淋巴结中MUC1基因mRNA的表达可以诊断肺癌隐匿性淋巴结转移.

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content