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find Keyword "原发性甲状腺功能亢进" 4 results
  • THE CLINICAL FEATURE OF GRAVES’ DISEASE ASSOCIATED WITH THYROID CANCER

    From 1972 to 1992, 333 patients underwent operations because of Graves’ disease in our hospital. Histological examination of resected thyroid tissue revealed carcinoma in 8 cases, which accounted for 2.4%(8/333). With reviewing the literatures basing on a lot of literature, we lay emphasis on the clinical feature of the disease, cause of misdiagnosis, and the diagnosis and treatment of the disease are discussed.

    Release date:2016-08-29 03:19 Export PDF Favorites Scan
  • Clinical Analysis of Primary Hyperthyroidism Complicated with Thyroid Carcinoma (Report of 15 Cases)

    Objective To analyze the clinical relationship between primary hyperthyroidism and thyroid carcinoma, and diagnosis and treatment for the combination of the two. Methods The clinical data of 15 patients with primary hyperthyroidism complicated with thyroid carcinoma from January 1998 to December 2008 were retrospectively analyzed. Results Fifteen cases were smoothly discharged. The morbidity was 2.56% (15/585) of primary hyperthyroidism complicated with thyroid carcinoma. There were no operative complications. Five cases showed thyroid nodules and all cases were performed thyroidectomy. Neither hyperthyroidism nor thyroid carcinoma recurred during 9 months to 10 years (average 5.5 years) follow-up.Conclusions The diagnosis of primary hyperthyroidism complicated with thyroid carcinoma is still difficult to be made preoperatively and chiefly depend on postoperative pathology. Rational surgical treatment can result in good effectiveness and better prognosis.

    Release date:2016-09-08 04:26 Export PDF Favorites Scan
  • Surgical Treatment of Primary Hyperthyroidism in Teenagers Patients (Report of 76 Cases )

    目的 探讨青少年原发性甲状腺功能亢进(甲亢)手术治疗的可行性。方法 本组76例甲亢患者手术麻醉以颈丛神经阻滞加强化为主; 手术方式为甲状腺大部分切除术,切除腺体组织约80%~90%,残留腺体总量约6~8 g。结果 无手术死亡及甲亢危象病例,术后10例(13.2%)发生并发症11例次,经保守治疗后症状消失。术后得到随访(1~15年)的51例患者中有6例于术后5~8年出现甲亢复发,无术后甲状腺功能低下病例。结论 手术治疗青少年甲亢具有快速安全、疗效持久、费用较低、患者愿意接受的特点,临床上是可行的。

    Release date:2016-09-08 11:45 Export PDF Favorites Scan
  • 地塞米松联合用药方案在原发性甲状腺功能亢进患者术前准备中的临床实践经验

    目的探讨地塞米松联合用药方案在原发性甲状腺功能亢进症(简称 “甲亢” )患者术前准备中应用的效果。方法回顾性收集郑州大学第一附属医院甲状腺外科2021年1月1日至2022年10月1日期间收治的原发性甲亢手术患者。采用地塞米松联合碘剂和β-受体阻滞剂联合应用的7 d术前准备方案(简称 “7 d方案” ):连续口服7 d复方碘溶液(3次/d,0.75 mL/次),在口服复方碘溶液的第5、6、7天时同时加用地塞米松注射液缓慢静脉滴注(1次/d,20 mg/次,上午10∶00开始,每次输入间隔时间24 h),手术前1 d口服β-受体阻滞剂普萘洛尔(剂量因人而异),于术前准备完成后第2天(第8天时)手术。观察入院时及使用地塞米松后的第1、2、3、4、5天时血清促甲状腺激素、游离三碘甲状腺原氨酸(free triiodothyronine,FT3)及游离甲状腺素(free thyroxine,FT4)水平的变化情况以及并发症情况。结果本研究共收集到58例患者,使用地塞米松后第1、2、3、4、5天时的FT3及FT4水平总体一直呈持续下降趋势(F=88.355,P<0.001;F=21.291,P<0.001),并且使用地塞米松后第2天开始FT3均值一直维持在正常水平,FT4均值虽未完全达到正常水平但比较接近正常水平;促甲状腺激素水平总体比较差异无统计学意义(χ2=1.607,P=0.900)。术后未发生甲状腺危象。结论从本研究结果看,“7 d方案”进行术前准备,较传统术前准备方法缩短了术前准备时间,对原发性甲亢的围术期管理安全、有效。

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