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find Keyword "双磷酸盐" 2 results
  • 双磷酸盐联合甲氨喋呤治疗绝经后类风湿关节炎患者疗效观察

    目的:评价双磷酸盐联合甲氨喋呤治疗绝经后类风湿关节炎患者疗效,分析治疗方法对类风湿关节炎活动度指标的影响。方法:选择2005~2007年我院住院及门诊的活动期类风湿关节炎患者75例,随机双盲分为2组,其中甲氨喋呤组45例,甲氨喋呤+双磷酸盐组30例。检测两组使用药物前后患者疾病活动性指标及血清中类风湿关节炎活动度相关指标,评价甲氨喋呤+双磷酸盐治疗方法的疗效。结果:甲氨喋呤+双磷酸盐治疗组可以提高骨密度,治疗后两组观察指标比较,甲氨喋呤+双磷酸盐组疾病活动度指标改善明显好于单用甲氨喋呤组。结论:双磷酸盐能有效防止骨丢失,帮助类风湿关节炎病情缓解。

    Release date:2016-09-08 10:02 Export PDF Favorites Scan
  • Curative Effects of Pulsed Electromagnetic Fields on Postmenopausal Osteoporosis

    We investigated the effects and optimal treatment frequency of pulsed electromagnetic fields (PEMFs) on postmenopausal osteoporosis (PMO). A comparison was performed with the cyclical alendronate and a course of PEMFs in the treatment for postmenopausal osteoporosis on bone mineral density (BMD), pain intensity and balance function. There was no significant difference between the two groups on mean percentage changes from baseline of BMD within 24 weeks after random treatments (P≥0.05). However, at the ends of 48 weeks and 72 weeks, the BMD of the PEMFs group were significantly lower than that of the alendronate group (P<0.05). No significant difference was detected between the two groups with regard to treatment effects on Visual Analogue Scale score, the Timed Up & Go Test and Berg Balance Scale score. Compared with cyclical alendronate, a course of PEMFs was as effective as alendronate in treating PMO for at least 24weeks. So its optimal treatment frequency for PMO may be one course per six months.

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