Objective To explore the clinical value of pleura biopsy and partial pleura cryobiopsy via electronic bronchoscope in diagnosis of unknown exudative pleural effusion. Methods Diagnostic results of 563 patients with unknown exudative pleural effusion were analyzed retrospectively. Bronchoscope and routine pleura biopsy were performed in 187 patients. Bronchoscope and routine pleura biopsy plus partial pleura cryobiopsy were performed in 376 patients. Pathological positive rates of the two groups were compared. Results In the 187 patients examined by bronchoscope and routine pleura biopsy from 2006 to 2008, 161 patients obtained pathological positive results ( 86.1% ) . In the 376 patients examined by bronchoscope and routine pleura biopsy plus partial pleura cryobiopsy from 2009 to 2012, 354 patients acquired pathological diagnosis ( 94.1% ) . There was significant difference between the two groups ( P lt; 0.05) . The main complications were bleeding and local chest pain, and they can be controlled easily. Conclusions Electronic bronchoscope and pleura biopsy can obtain high detection rate of nearly 90% in diagnosis of unknown exudative pleural effusion especially when combined with cryobiopsy of partial pleura. Electronic bronchoscope combined with pleura biopsy or cryobiopsy is an alternative in clinical settings when thoracoscope is unavailable.
ObjectiveTo compare the effect of three different wetting liquid supply modes for noninvasive ventilation. MethodsNinety patients who accepted noninvasive ventilation between February and October 2014 were randomly divided into three groups with 30 in each. Patients in group A underwent humidification with traditional kettle water; those in group B received humidification by one-time automatic water supplying; and patients in group C received continuous infusion to add water for humidification. The wetting effect and humidification related situations among the three groups of patients were compared and analyzed. ResultsThere were statistically significant differences among the three groups in terms of wetting effect, comfort degree, water renewal cycle, working time and economic cost (P<0.05). Good wetting rate of group C was superior to group A and B (P<0.05), but there was no statistically significant difference between group A and B (P>0.05). Humidification comfort degree of group C was obviously higher than that in group A and B (P<0.05), while there was no statistically significant difference between group A and B (P>0.05). Water renewal cycle and working time of group C were significantly shorter than those in group A and B (P<0.05). At the same time, economic cost of group A and C was significantly less than that of group B (P<0.05), while there was no statistically significant difference between group A and C (P>0.05). ConclusionThe kind of continuous infusion for humidification in noninvasive ventilation has a good therapeutic effect for patients receiving airway wetting therapy, which is worthy of clinical popularization and application.
ObjectiveTo study and compare the effects of inhaled preparations with open airway and conventional inhaled preparation on asthma patients.MethodsThe patients diagnosed with asthma and treated with the same inhaled preparation only who visited the outpatient department of West China Hospital of Sichuan University, were selected as the study subjects from April to September, 2019. The subjects were divided into the test group and the control group according to random ratio 1∶1. The conventional inhaled preparations were used in the control group. The inhaled preparations with open airway were used in the test group. Asthma control, life quality and treatment satisfaction rate were compared between the two groups after 3 months.ResultsA total of 150 subjects were included and one case dropped-off, then 149 effective subjects were obtained in which 75 cases in the test group and 74 cases in the control group. After 3 months’ treatment of inhaled preparations, the proportion of effective asthma control patients in the test group was higher than that in the control group, and the number of patients satisfied with the treatment of inhaled preparations was higher than that in the control group, with statistically significant differences (all P<0.05). The life quality of patients in both groups was improved compared with baseline, and the difference was statistically significant (P<0.05). However, the increase of scores in the test group was more than that in the control group, and the difference was also statistically significant (P<0.05). ConclusionInhaed preparations with open airway is superior to conventional inhaled preparation on asthma patients in asthma control, life quality and treatment satisfaction rate.