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find Author "吴晓东" 5 results
  • 气道防御屏障

    人类气道从功能上可以分为四个解剖节段: 上呼吸道( 鼻咽部, Ⅰ段) 、导气段( 从咽到终末支气管, Ⅱ 段) 、呼吸性支气管( Ⅲ段) 、肺泡管和肺泡( Ⅳ段) 。随着管径变细, 气道上皮逐渐由假复层上皮变为单层上皮, 上皮细胞的高度也逐渐变低, 杯状细胞数量逐渐变少直至消失。其结构不同, 决定了功能的不同。肺泡是进行气体交换的场所, 表面只覆有单层肺泡上皮细胞, 容易受到外界微生物或吸入颗粒的损伤, 因此Ⅰ、Ⅱ和Ⅲ段气道的主要功能是净化吸入气体, 降低肺泡接触损伤因素的可能性, 从而维持肺泡正常气体交换功能。Ⅰ段可清除直径gt; 10 μm的颗粒,Ⅱ、Ⅲ段可清除直径gt;0. 5 μm的颗粒, 直径lt; 0. 5 μm的颗粒可进入肺泡。为保障在清除过程中空气中抗原物质不至于引起气道损伤或感染,气道黏膜存在着屏障功能。我们提出用“气道防御屏障”来概括各种屏障因素。该屏障不仅包括以前所认为的由黏液冲刷、纤毛运动以及气道上皮的紧密连接组成的简单的机械屏障, 而且包括由多种免疫细胞和气道上皮细胞参与的免疫屏障。

    Release date:2016-09-13 04:07 Export PDF Favorites Scan
  • Exploration of in-vitro diagnostic reagent purchasing management based on knowledge

    In order to meet the rapid development of in-vitro diagnostic reagent (IVD) market and the development needs of laboratory medicine, and ensure efficient management and cost control in IVD purchasing, it is necessary to build the purchasing management standard, improve the purchasing quality of IVD, reduce the overall hospital costs, and ensure the accuracy and reliability of clinical test results. Through three aspects: the preparation before business negotiation, business negotiation, and execution after business negotiation, this article clarifies the self-bidding procurement process of IVD, and emphasizes the importance of knowledge in IVD procurement management, so as to provide references and suggestions for novice buyers to get familiar with the business quickly and improve their negotiation ability.

    Release date:2019-06-25 09:50 Export PDF Favorites Scan
  • Construction practice of medical supplies access management system based on evidence

    As the reform of medical insurance payment methods is implemented, it is necessary for the medical institutions to further improve cost control and standardize the rational use of medical supplies. Over the years, West China Hospital of Sichuan University has made the assessment of the access of supplies by using the existing external evidence and the internal evidence created through real world data analysis methods. In this thesis, the difficulties faced by the access of medical supplies are deeply analyzed. The supplies access management system of West China Hospital of Sichuan University and its achievements in average waiting time of new supplies, rationality of purchase application, scientificity of demonstration results, support for the implementation of fourth-level surgery, and cost control are taken as examples. From this, a set of new paths can be provided for other hospitals to learn from at the time of carrying out medical supplies access management.

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  • Risk and Quality Control of Medical Instruments

    Theory of risk control was introduced to medical instruments quality control management in West China Hospital. A quality control system for the whole life cycle management of instruments has been established, which includes evaluation before instrument purchase, policy and management of bidding, operation training, safe maintenance, maintenance management and waste disposal. Medical instrument quality system was introduced to provide information for medical instrument risk control and quality management in a large, general Chinese hospital.

    Release date:2016-09-07 11:23 Export PDF Favorites Scan
  • Ten measures to fight against the 2019-nCoV pneumonia in West China Hospital

    After the occurrence of public health emergencies, as the most direct front position, how to carry out medical treatment orderly, effectively, rapidly and safely in a short time has become the focus and difficulty of epidemic control. After the outbreak of 2019 novel coronavirus pneumonia (2019-nCoV), West China Hospital of Sichuan University, as a large-scale general hospital under the supervision of the CPC central committee, put people's life safety and health first, and attach great importance to the prevention and control of the epidemic. This paper introduces the ten measures taken by West China Hospital of Sichuan University to fight against the 2019-nCoV pneumonia, in order to provide reference for other hospitals.

    Release date:2020-04-18 07:22 Export PDF Favorites Scan
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