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find Author "吴畏" 3 results
  • Enhancing the research on three-dimensional culture of embryonic stem cells to optimize the strategy to make the seed cells

    There are over 8 million blind patients in China, 1/3 of them are suffered from retinal degeneration diseases. Stem cells transplantation can delay the photoreceptor cell degeneration or replace the dead photoreceptor cells, provides hopes for these patients. How to make enough seed cells is the major barrier for cell therapy. Good seed cells should be safe and with great pluripotency, and can be made from a wide range of sources, easy to be standardized and industrialized. Seed cells made from three-dimensional embryonic stem cells cultures can reach the above criteria, thus three-dimensional embryonic stem cell culture is a new strategy for making seed cells for cell treatment of blind diseases.

    Release date:2016-11-25 01:11 Export PDF Favorites Scan
  • Effects of Propofol on Serum Inflammatory Cytokines in Operative Patients with Hypertensive Brain Bleeding

    目的 明确异丙酚对于高血压脑出血患者血清炎性细胞因子的影响。 方法 将2008年3月-2009年3月收治的高血压脑出血患者47例分为两组,异丙酚组采用异丙酚、芬太尼、维库溴铵以及异氟醚诱导和维持麻醉;对照组采用依托咪酯、芬太尼、维库溴铵以及异氟醚诱导和维持麻醉。比较两组患者手术中不同时段血清白细胞介素(IL-6)、肿瘤坏死因子(TNF)、血栓素、内皮素、前列腺素E和降钙素水平。 结果 患者麻醉过程中生命体征平稳,无麻醉相关死亡。术前异丙酚组患者血清IL-6、TNF、血栓素、内皮素、前列腺素E和降钙素水平与对照组比较均无差异(P>0.05),而麻醉诱导后差异有统计学意义(P<0.05),而且差异随时间延长增大。 结论 采用异丙酚麻醉能降低术中血清炎性细胞因子水平。

    Release date:2016-09-08 09:47 Export PDF Favorites Scan
  • 负压封闭引流在乳腺癌改良根治术后腋窝引流中的应用价值

    目的评价负压封闭引流(VSD)在乳腺癌改良根治术后腋窝引流中的应用效果。 方法收集 2017 年 1 月至 2018 年 2 月期间达州市中心医院乳腺甲状腺外科收治的 128 例行乳腺癌改良根治术患者的临床资料(均为女性),其中胸壁及腋窝均使用普通硅胶管引流患者 60 例(对照组),胸壁使用普通硅胶管而腋窝使用去除吸附泡沫材料的 VSD 装置患者 68 例(观察组),比较 2 组患者的术后腋窝拔管时间以及腋窝皮瓣感染、腋窝积液和皮瓣坏死及切口愈合情况。 结果与对照组比较,观察组的腋窝拔管时间明显更早(Z=–3.340,P=0.001),腋窝皮瓣感染率(χ2=4.486,P=0.034)和腋窝积液率(χ2=5.901,P=0.015)更低,切口甲级愈合率更高(χ2=11.715,P=0.001),而 2 组术后腋窝皮瓣坏死率比较差异无统计学意义(χ2=0.483,P=0.487)。 结论乳腺癌改良根治术后腋窝使用 VSD 能降低患者术后腋窝并发症的发生率。

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