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find Author "唐金海" 3 results
  • Single Nucleotide Polymorphism and Chemotherapy Response of Breast Cancer

    Objective To investigate the relationship between single nucleotide polymorphism (SNP) and therapy response of some conventional chemotherapy drugs in breast cancer, and to explore the value of SNP in guiding individualized treatment. Methods Pub-Medline and Chinese CHKD periodical electronic databases were searched. Representative researches in this field were sorted out and concluded. Results Varied genes related to drug metabolism have SNP phenomenon, which are closely associated with interindividual diversity in drug response. Race, section, environment, and drug-drug or gene-gene interactions may have effect on the association.Conclusion The study on SNP has important application prospect in optimizing the individual drug-delivery. However, the combinatorial analyses of multi-SNPs and multi-genes and the prospective studies with large-scale samples and random controls are still needed.

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  • Development of Diagnosis and Surgical Treatments for Early Breast Cancer

    Release date:2016-09-08 10:42 Export PDF Favorites Scan
  • Application of Molecular Targeted Drugs in Neoadjuvant Treatment of Breast Cancer

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