Ｎｉｎｅｔｙ ｃａｓｅｓ ｏｆ ｓｕｒｇｉｃａｌｌｙ ｔｒｅａｔｅｄ ｒｅｃｕｒｒｅｎｔ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａ ｉｓ ｒｅｐｏｒｔｅｄ ｗｉｔｈ ａｎａｌｙｓｉｓ ｏｆ ｔｈｅ ｍａｃｈａｎｉｓｍ ｏｆ ｒｅｃｕｒｒｅｎｃｅ ａｎｄ ｆａｃｔｏｒｓ ａｆｆｅｃｔｉｎｇ ｔｕｍｏｒ ｒｅｃｕｒｒｅｎｃｅ． Ｅａｒｌｙ ｄｅｔｅｃｔｉｏｎ ｏｆ ｒｅｃｕｒｒｅｎｃｅ ｄｅｐｅｎｄｓ ｏｆ ＡＦＰ ｍｅａｓｕｒｅｍｅｎｔｓ ａｎｄ ｕｌｔｒａｓｏｎｏｇｒａｐｈｙ ｆｏｌｌｏｗｕｐ ｍｏｎｉｔｏｒｉｎｇ ａｆｔｅｒ ｒｅｓｅｃｔｉｏｎ． Ｈｅｐａｔｉｃ ｒｅｓｅｃｔｉｏｎ ｉｓ ｔｈｅ ｆｉｒｓｔ ｃｈｏｉｃｅ ｏｆ ｔｒｅａｔｍｅｎｔ ｗｈｅｎｅｖｅｒ ｉｔ ｉｓ ｆｅａｓｉｂｌｅ． Ｉｎｔｒａｔｕｍｏｒ ｅｔｈａｎｏｌ ｉｎｊｅｃｔｉｏｎ ａｎｄ ｔｒａｎｓｃａｔｈｅｔｅｒ ａｒｔｅｒｉａｌ ｃｈｅｍｏｅｍｂｏｌｉｚａｔｉｏｎ ｄｕｒｉｎｇ ｏｐｅｒａｔｉｏｎ ｈａｓ ｂｅｅｎ ｂｅｎｅｆｉｃｉａｌ ｉｎ ｓｏｍｅ ｐａｔｉｅｎｔｓ ｗｉｔｈ ｕｎｒｅｓｅｃｔａｂｌｅ ｒｅｃｕｒｒｅｎｔ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａ． Ｔｈｅｓｅ ｒｅｓｕｌｔｓ ｓｕｇｇｅｓｔ ｔｈａｔ ｒｅｏｐｅｒａｔｉｏｎ ｆｏｒ ｒｅｃｕｒｒｅｎｔ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａ ｍａｙ ｂｅ ａｎ ａｐｐｒｏａｃｈ ｔｏ ｉｍｐｒｏｖｅ ｔｈｅ ｌｏｎｇｔｅｒｍ ｓｕｒｖｉｖａｌ ａｆｔｅｒ ｈｅｐａｔｉｃ ｒｅｓｅｃｔｉｏｎ．
ObjectiveTo summarize the current comparison of the efficacy of different treatments for recurrent hepatocellular carcinoma.MethodTo search the literatures about the comparative studies on the efficacy of different treatments for recurrent hepatocellular carcinoma in recent years and analyze them.ResultsIn the treatment of recurrent hepatocellular carcinoma, percutaneous arterial chemoembolization combined with radiofrequency ablation could improve the survival rate and tumor-free survival rate to some extent, compared with the single use of percutaneous arterial chemoembolization. In the short term, there was no difference in efficacy between radiofrequency ablation and surgical resection, but the local recurrence rate of radiofrequency ablation was higher than that of surgical resection group. Salvage liver transplantation offered potential opportunity to reduce the risk of recurrence and tended to improve long-term survival outcomes, but liver sources were scarce and costly. ConclusionsAt present, there is no systematic staging scheme and treatment system for recurrent hepatocellular carcinoma. At the same time, most studies are retrospective, and more prospective studies are needed to further explore the treatment of recurrent hepatocellular carcinoma.