早在1757年法国LeDran即说过有希望“治愈”乳腺癌,历经三个多世纪,乳腺癌的诊治虽已发生很大的变化,但依然是危害女性的重要疾病之一,至今尚未能解释乳腺癌的全部生物行为,也无统一的理想治疗方案。现将乳腺癌诊治进展介绍如下。
【Abstract】Objective To investigate the effect of donor blood transfusion on inducing pancreatic allograft tolerance in outbred rat model. Methods Wistar male rats were used as blood and pancreas donor, and diabetic recipients. One ml of donor blood injected into abdomen of diabetic recipients on the day of transplantation and azathioprine given 2 days pretransplant and continued for three days. Results Pancreas allograft survival was significantly prolonged (28 to 112 days, media survival time 64.2 days). One ml of donor blood alone injected into the abdomen and azathioprine given alone 2 days pretransplant did not improve allograft survival (media survival time 9.8 vs 10.2 days). Conclusion Donor blood injected on the day of transplantation and a 3 days course of azathioprine started 2 days pretransplant have b synergism in inducing long term graft survival in this rat model.