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find Author "孙彦隽" 4 results
  • Cryopreserved Homograft Pericardium Patch in Staged Repair of Tetralogy of Fallot

    Objective To compare the difference of effect while using homograft pericardium patch and Gore- tex patch in staged repair of tetralogy of Fallot(TOF) to enlarge the right ventricular outflow tract (RVOT). Methods Twenty-eight patients with TOF who underwent the staged complete repair were divided into 2 groups according to the date of surgery. Gore-rex group, 13 cases, their RVOT were enlarged with Gore-tex patches. Cryopreserved homograft pericardium patch group, 15 cases, their RVOT were enlarged with cryopreserved homograft pericardium patches. Clinical results and follow-up results were compared. Results There were 1 operative death in Gore-tex patch group (7. 7%), and 1 early postoperative death in cryopreserved homograft pericardium patch group (6. 7%). Hemostasia time, the pericardial cavity drainage volume in cryopreserved homograft pericardium patch group were less than those in Gore-tex patch group (P〈0. 01). All patients were followed-up for 0.8-4.5years. The residual obstruction rate at RVOT level in Gore-tex patch group was higher than that in cryopreserved homograft pericardium patch group by echocardiography (P〈0.01). No calcification shadow was found on the chest X-ray. Conclusion Homograft pericardium is the tissue with high density and intensity, its elasticity and compliance are good. Using homograft pericardium patch may be helpful to decrease the residual obstruction of RVOT after operation. It can be adapted as a repairing material in heart surgery.

    Release date:2016-08-30 06:26 Export PDF Favorites Scan
  • 低温保存对山羊大动脉细胞形态的影响

    目的 观察低温保存过程对山羊动脉细胞形态的影响. 方法 将12段山羊动脉按不同的降温速率分成4组,分别用透射电子显微镜和扫描电子显微镜观察冻存前后的动脉细胞形态. 结果 与正常血管组织相比,0.5 K/min组和0.1 K/min组虽细胞间连接紧密,但内皮细胞附着松散,出现大的空泡,有的平滑肌细胞肿胀,细胞质苍白多水,线粒体收缩;还有的虽平滑肌细胞轻微肿胀,但细胞器肿胀严重破坏. 5 K/min组和2 K/min组内皮细胞与基膜大量脱离,内皮细胞和平滑肌细胞破坏严重,出现核溶解及线粒体一些不能恢复的变化. 结论 经低温保存后的山羊主动脉与新鲜组织的区别明显,细胞组织形态被破坏,低温保存的降温速率越快,破坏越严重.

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
  • Application of Ozaki operation in treatment of aortic regurgitation in children

    ObjectiveTo explore the early results of Ozaki operation in children with aortic regurgitation.MethodsWe retrospectively analyzed the clinical data of 15 patients with aortic regurgitation who received the Ozaki operation in our hospital from April 2017 to July 2019. There were 11 males and 4 females with an average operation age of 10.7±3.7 years. Besides preoperative evaluation, aortic regurgitation and cardiac function were evaluated on 1 day, 1 week, 1 month, 3 months, and 6-12 months after surgery.ResultsIn 14 (93.3%) patients , the aortic valve leaflets functioned well on 1 day, 1 month, 3 months, and 6-12 months, and the regurgitation grade was Ⅰ-Ⅱ, which was improved than before (P=0.001). The cardiac function of children recovered quickly after operation. There was no statistical difference in ejection fraction on 1 day, 1 month, 3 months, and 6-12 months after operation (P>0.05). No children died, and no other clinical event was found.ConclusionThe Ozaki technique of reconstructing a tricuspid aortic valve leaflet for the treatment of severe aortic regurgitation in children is effective in short term, and the persistence of its valve function remains to be determined in the long-term follow-up.

    Release date:2020-12-07 01:26 Export PDF Favorites Scan
  • Surgical treatment strategy and outcome of functional univentricular heart with total anomalous pulmonary vein drainage

    Objective To explore the surgical management method and outcome of functional univentricular heart with total anomalous pulmonary vein drainage (UVH-TAPVD). Methods We reviewed the surgical procedures and results for 44 UVH-TAPVD patients in our hospital between the year 2010 and 2016. There were 34 males and 10 females. The age of the patients was 312 (77-4 220) d when they accepted the first surgical treatment. Results There were 8 deaths in stage Ⅰ palliation, 1 death in stage Ⅱ palliation and 5 deaths during the follow-up. The overall survival rate was 68.2% (30/44). Glenn operation was undertaken in 34 patients with 5 deaths. Fontan operation was undertaken in 9 patients with 2 deaths. Conclusion Surgical strategies for UVH-TAPVD should be planned according to different anatomical and pathophysiological conditions in different patients. Staged palliations can reduce mortality and morbidity. But pulmonary venous obstruction and heterotaxy syndrome are still risk factors for these patients.

    Release date:2018-01-31 02:46 Export PDF Favorites Scan
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