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find Author "安国营" 3 results
  • Experimental Research on Sheep Mitral Valves Replacement with Stentedpulmonary Autograft

    Objective To investigate the feasibility and effect of stentedpulmonary autograft replacement and find out the best way to treat mitral valve diseases. Methods From August 2006 to October 2007, 20 male sheep at the age of about 1 year old underwent mitral valves replacement operation in Anzhen Hospital. Weight of these sheep was 50.0±6.0 kg. They were randomly divided into two groups. Ten sheep in the experimental group underwent RossⅡsurgery in which we first sutured pulmonary valve onto a pulmonary valve stent, transferred the valve to the mitral valve annulus and then reestablished the outflow tract of the right ventricle. The other 10 sheep in the control group underwent bioprosthetic valve replacement routinely. Ultrasonic cardiogram (UCG) was employed 6 hour after operation to measure the effective orifice area (EOA) of the mitral valve, mitral peak velocity of early filling, the peak pressure gradient (PPG), the extent of regurgitation, left ventricular enddiastolic dimension (LVEDD) and ejection fraction (EF). Results One sheep in the experimental group died of low cardiac output syndrome; one in the control group died of unmanageable bleeding during operation, and the others all survived. Six hours after operation, UCG of the experimental group showed that the heart valves were well fixed, valve echo was clear, and there was no perivalvular leakage or mitral valve stricture or regurgitation, but moderate pulmonary valve regurgitation occurred in 1 case and mild in 2. There was no significant difference between the two groups in PPG (11.86±1.28 mm Hg vs. 10.98±0.98 mm Hg,t= 1.670,P=0.110) and the mitral peak velocity of early filling (1.72±0.09 m/s vs. 1.65±0.07 m/s, t=1.680,P=0.110). However, EOA of the experimental group was smaller than the control group (2.23±0.09 cm2 vs. 2.39±0.08 cm2, t= 4.240,P= 0.001). Conclusion The experimental result of sheep mitral valves replacement with stentedpulmonary autograft is satisfying. The new mitral valves work well and the surgery method is feasible.

    Release date:2016-08-30 06:02 Export PDF Favorites Scan
  • 右腋下小切口体外循环心内直视手术270例

    目的 总结右腋下小切口在常见先天性心脏病手术中的应用经验。 方法 回顾性分析济宁医学院附属医院2009年10月至2011年6月采用右腋下小切口经第4肋间进胸,在体外循环下施行心内畸形矫治手术270例患者的临床资料,其中男132例,女138例;年龄3个月~9岁 (3.0±1.6) 岁,行室间隔缺损(VSD)修补术132例,房间隔缺损(ASD)修补术50例,ASD修补术+部分型肺静脉异位引流(PAPVC)矫治术12例,部分型房室管畸形(PECD)矫治术15例,VSD+ASD修补术26例,法洛四联症根治术35例。 结果 全组无手术死亡,无二次开胸止血,平均住院时间9 d,平均住ICU 1.6 d。发生右肺不张3例,右侧气胸2例,阵发性室上性心动过速1例,Ⅱ°房室传导阻滞1例。术后全部患者均获得随访,随访时间1~16个月,随访期间3例VSD术后发生小于2 mm的残余漏,其余患者恢复良好。 结论 对具有该术式适应证的患者经右腋下小切口行心内直视手术,有安全可靠、创伤小、美观等优点。

    Release date:2016-08-30 05:50 Export PDF Favorites Scan
  • Cardiac Valvular Surgery for 129 Patients by Small Incision at the Third Intercostal Space via Right Anterolatera

    目的总结右胸前第3肋间小切口瓣膜置换/成形术的技术要点。 方法回顾性分析2011年1月至2014年6月我院行右胸前第3肋间小切口心脏瓣膜手术129例的临床资料,其中男57例、女72例,年龄23~65(42±17)岁。瓣膜病变患者股动静脉插管建立体外循环、经右胸前第3肋间小切口行瓣置换/成形术,其中行二尖瓣置换术49例,二尖瓣成形术21例,主动脉瓣置换术33例,二尖瓣+主动脉瓣双瓣膜置换术26例。 结果129例手术均顺利完成,切口长度5~7 cm,无感染及神经系统并发症发生,住院时间10~14 d,均痊愈出院。随访1~30个月,患者心功能改善,无死亡病例。 结论右胸前第3肋间小切口行瓣膜手术安全可靠,创伤小并具有美容效果。

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