【摘要】 目的 系统评价丹参酮治疗寻常痤疮的疗效和安全性。 方法 计算机检索Cochrane图书馆、PubMed、EMBase、CBM、VIP、CNKI数据库，起止时间均从建库至2009年9月。手工检索其他皮肤病相关杂志。对纳入的丹参酮治疗寻常痤疮的随机对照试验（RCT）进行质量评价，并进行Meta分析。 结果 共纳入11个RCT，但其质量普遍不高。Meta分析结果显示，丹参酮在治疗寻常痤疮相比于抗生素治疗，其有效率明显高于对照组，有统计学意义[RR=1.38，95%CI（1.25，1.51），Plt;0.000 01]，其不良反应发生概率明显低于对照组，统计学意义[OR=0.32，95%CI（0.22，0.46），Plt;0.000 01]。 结论 丹参酮治疗寻常痤疮的疗效和安全性优于抗生素治疗。但由于纳入研究少，研究质量普遍不高，上述结果有待高质量大样本的随机双盲对照试验加以验证。【Abstract】 Objective To assess the efficacy and safety of danshinone in the treatment of acne vulgaris. Methods The Cochrane Library, PubMed, EMBase,CBM,VIP and CNKI database were searched from established time to September 2009. Manual testing other dermatosis related magazines. Randomized controlled trails (RCTs) that included were evaluated and analyzed by the software RevMan 5.0. Results Eleven studies were included,but their quality were not high. The result of Meta analysis demonstrated that there were statistical differences of indexes between groups as total effective rate [RR=1.38, 95%CI (1.25,1.51),Plt;0.000 01] and adverse reactions [OR=0.32,95%CI(0.22,0.46),Plt;0.000 01]. Conclusions The preliminary results of the system evaluation indicates that danshinone is safe and effective for acne vulgaris. However, due to the limited quantity and quality of the included studies, the results suggest that further and larger-scale trials using tanshinone for acne vulgaris are needed.